ID Q6ZY54_KLEPN Unreviewed; 263 AA. AC Q6ZY54; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 25-NOV-2008, entry version 25. DE SubName: Full=Beta-lactamase; DE Flags: Fragment; GN Name=blaLEN; OS Klebsiella pneumoniae. OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Klebsiella. OX NCBI_TaxID=573; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=UD827:1; RX PubMed=15215087; DOI=10.1128/AAC.48.7.2400-2408.2004; RA Haeggman S., Loefdahl S., Paauw A., Verhoef J., Brisse S.; RT "Diversity and evolution of the class A chromosomal beta-lactamase RT gene in Klebsiella pneumoniae."; RL Antimicrob. Agents Chemother. 48:2400-2408(2004). CC -!- CATALYTIC ACTIVITY: A beta-lactam + H(2)O = a substituted beta- CC amino acid. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ635424; CAG25835.1; -; Genomic_DNA. DR HSSP; P00807; 1ALQ. DR SMR; Q6ZY54; 11-263. DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro. DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro. DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro. DR InterPro; IPR001466; Beta_lactamase-related. DR InterPro; IPR000871; Beta_lactamase_A/D. DR Pfam; PF00144; Beta-lactamase; 1. DR PRINTS; PR00118; BLACTAMASEA. DR PROSITE; PS00146; BETA_LACTAMASE_A; 1. PE 4: Predicted; KW Antibiotic resistance; Hydrolase. FT NON_TER 1 1 FT NON_TER 263 263 SQ SEQUENCE 263 AA; 28331 MW; 7A71E3F2267930B8 CRC64; ATLPLVVYAG PQPLEQIKQS ESQLPGRVGM VEMDLASGRT LAAWRADERF PMVSTFKVLL CGAVLARVDA GLEQLDRRIH YRQQDLVDYS PVSEKHLVDG MTIGELCAAA ITLSDNSAGN LLLATVGGPA GLTAFLRQIG DNVTHLDRWE TALNEALPGD ARDTTTPASM AATLRKLLTA QHLSARSQQQ LLQWMVDDRV AGPLIRAVLP PGWFIADKTG AGERGARGIV ALLGPDGKPE RIVVIYLRDT PASMAERNQH IAG //