ID Q6WNT0_TAKRU Unreviewed; 461 AA. AC Q6WNT0; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 11-DEC-2019, entry version 70. DE SubName: Full=Transcription factor Sox8b {ECO:0000313|EMBL:AAQ18506.1}; GN Name=Sox8b {ECO:0000313|EMBL:AAQ18506.1}; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu. OX NCBI_TaxID=31033 {ECO:0000313|EMBL:AAQ18506.1}; RN [1] {ECO:0000313|EMBL:AAQ18506.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=15019997; DOI=10.1016/j.gene.2003.12.008; RA Koopman P., Schepers G., Brenner S., Venkatesh B.; RT "Origin and diversity of the SOX transcription factor gene family: genome- RT wide analysis in Fugu rubripes."; RL Gene 328:177-186(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY277963; AAQ18506.1; -; Genomic_DNA. DR eggNOG; ENOG410IPZC; Eukaryota. DR eggNOG; ENOG4111PMB; LUCA. DR HOGENOM; HOG000108876; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro. DR Gene3D; 1.10.30.10; -; 1. DR InterPro; IPR009071; HMG_box_dom. DR InterPro; IPR036910; HMG_box_dom_sf. DR InterPro; IPR031265; SOX-8. DR InterPro; IPR022151; Sox_N. DR PANTHER; PTHR45803:SF2; PTHR45803:SF2; 1. DR Pfam; PF00505; HMG_box; 1. DR Pfam; PF12444; Sox_N; 1. DR SMART; SM00398; HMG; 1. DR SUPFAM; SSF47095; SSF47095; 1. DR PROSITE; PS50118; HMG_BOX_2; 1. PE 4: Predicted; KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267, KW ECO:0000256|SAAS:SAAS00879239}; KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267}. FT DOMAIN 91..159 FT /note="HMG box" FT /evidence="ECO:0000259|PROSITE:PS50118" FT DNA_BIND 91..159 FT /note="HMG box" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267" FT REGION 1..52 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 163..188 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 207..252 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 321..398 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 442..461 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 10..28 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 340..354 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 377..398 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 461 AA; 50452 MW; 1305FC61E64606A6 CRC64; MKEDCHSLTY SPPSPGTKAS MSQSASDSEF PNDKDKSDSA GVITQRSPSS AEDRFPVCIR DAVSQVLKGY DWSLVAVSAP GERGLKNKPH VKRPMNAFMV WAQAARKKLA DQYPHLHNAE LSKTLGKLWR LLTETEKRPF IEEADRLRMQ HKKTYPDYKY QPRRRKVTKV GEGDCRPGST QQQDGLCKTE TTMKLPSAGE VHSYYHQDRA GQSNGPPTPP STPKPDVHMG TTREVHRPSD GGSIPPTSRQ NIDFSNVDIS DLSTDVIGTI DGFDVHEFDQ YLTPNSHGST ALPPSDTGHG YLNPPGAFIL PNIHSHSIPT WTRKSPALTG MPSCDKPTLS EDTTTRKPLV KTEQMSPDHH SGSCTSPPPP LQPQCTPGSS VCPSSASSPS STRPPDYSDL QSSSFFSAIS GYVPPLYQHP YFHPSCVSYA TPLINSLALA PPSHSPPSGW EQPIYTTLTK P //