ID Q6RWF2_9ZZZZ Unreviewed; 344 AA. AC Q6RWF2; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 22-FEB-2023, entry version 35. DE SubName: Full=Nitrilase {ECO:0000313|EMBL:AAR97497.1}; DE EC=3.5.5.7 {ECO:0000313|EMBL:AAR97497.1}; GN ORFNames=BD7031 {ECO:0000313|EMBL:AAR97497.1}; OS uncultured organism. OC unclassified sequences; environmental samples. OX NCBI_TaxID=155900 {ECO:0000313|EMBL:AAR97497.1}; RN [1] {ECO:0000313|EMBL:AAR97497.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=15066841; DOI=10.1128/AEM.70.4.2429-2436.2004; RA Robertson D.E., Chaplin J.A., DeSantis G., Podar M., Madden M., Chi E., RA Richardson T., Milan A., Miller M., Weiner D.P., Wong K., McQuaid J., RA Farwell B., Preston L.A., Tan X., Snead M.A., Keller M., Mathur E., RA Kretz P.L., Burk M.J., Short J.M.; RT "Exploring nitrilase sequence space for enantioselective catalysis."; RL Appl. Environ. Microbiol. 70:2429-2436(2004). CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily. CC Nitrilase family. {ECO:0000256|ARBA:ARBA00008129}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY487550; AAR97497.1; -; Genomic_DNA. DR AlphaFoldDB; Q6RWF2; -. DR GO; GO:0018762; F:aliphatic nitrilase activity; IEA:UniProtKB-EC. DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro. DR CDD; cd07564; nitrilases_CHs; 1. DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1. DR InterPro; IPR003010; C-N_Hydrolase. DR InterPro; IPR036526; C-N_Hydrolase_sf. DR InterPro; IPR000132; Nitrilase/CN_hydratase_CS. DR InterPro; IPR044149; Nitrilases_CHs. DR InterPro; IPR023919; Nitrile-rel_sll0784. DR PANTHER; PTHR46044:SF1; CN HYDROLASE DOMAIN-CONTAINING PROTEIN; 1. DR PANTHER; PTHR46044; NITRILASE; 1. DR Pfam; PF00795; CN_hydrolase; 1. DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1. DR TIGRFAMs; TIGR04048; nitrile_sll0784; 1. DR PROSITE; PS50263; CN_HYDROLASE; 1. DR PROSITE; PS00921; NITRIL_CHT_2; 1. PE 3: Inferred from homology; KW Hydrolase {ECO:0000313|EMBL:AAR97497.1}. FT DOMAIN 7..273 FT /note="CN hydrolase" FT /evidence="ECO:0000259|PROSITE:PS50263" SQ SEQUENCE 344 AA; 37809 MW; CC2552F4806403EF CRC64; MSDRRIVRAA AIQIAPDLER CSVTLEKVCS AIDEAAGKGA QLSVFPETFV PYYPYFSFVR PPVASGADHM RLYEEAVVVP GPVTQAVSER ARMHGMVVVL GVNERDHGSL YNTQLIFDCD GRLALKRRKI TPTFHERMIW GQGDASGLKV ARTGIGRVGA LACWEHYNPL ARYALMTQHE EIHCSQFPGS LVGPIFSEQM DVTIRHHALE SGCFVVNATG WLTDAQIASI TDDPKLQRAL RGGCNTAIVS PEGQHLAEPL REGEGMVVAD LDMSLITKRK RMMDSVGHYA RPELLSLAIN DRPAAPFGRM CAAEAMRGAD DVVTVGAFHE RQRERVGEEP AIDD //