ID Q6R5J6_RAT Unreviewed; 275 AA. AC Q6R5J6; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 16-MAR-2016, entry version 75. DE SubName: Full=NYGGF5 {ECO:0000313|EMBL:AAR97577.1}; DE SubName: Full=Protein Slc25a27 {ECO:0000313|Ensembl:ENSRNOP00000039207}; GN Name=Slc25a27 {ECO:0000313|Ensembl:ENSRNOP00000039207, GN ECO:0000313|RGD:620787}; GN Synonyms=Nyggf5 {ECO:0000313|EMBL:AAR97577.1}; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116 {ECO:0000313|EMBL:AAR97577.1}; RN [1] {ECO:0000313|EMBL:AAR97577.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Sprague-Dawley {ECO:0000313|EMBL:AAR97577.1}; RA Gui X., Ni Y., Zhang M., Wang B., Gong H., Fei L., Qian L., Zhao Y., RA Chi X., Chen R., Guo M., Pan X., Zhou M., Hong H., Tan Z.; RT "A new gene cloned from the cDNA library of rat adipose tissue."; RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSRNOP00000039207, ECO:0000313|Proteomes:UP000002494} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000039207, RC ECO:0000313|Proteomes:UP000002494}; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [3] {ECO:0000313|Ensembl:ENSRNOP00000039207} RP IDENTIFICATION. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000039207}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) CC family. {ECO:0000256|RuleBase:RU000488}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AABR07066866; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AY512661; AAR97577.1; -; mRNA. DR UniGene; Rn.163043; -. DR STRING; 10116.ENSRNOP00000039207; -. DR Ensembl; ENSRNOT00000052068; ENSRNOP00000039207; ENSRNOG00000010592. DR RGD; 620787; Slc25a27. DR eggNOG; KOG0753; Eukaryota. DR eggNOG; ENOG410XRV1; LUCA. DR GeneTree; ENSGT00760000119170; -. DR HOVERGEN; HBG009528; -. DR OrthoDB; EOG7MSMPK; -. DR TreeFam; TF354328; -. DR Reactome; R-RNO-167826; The fatty acid cycling model. DR Reactome; R-RNO-167827; The proton buffering model. DR Proteomes; UP000002494; Chromosome 9. DR GO; GO:0045177; C:apical part of cell; IDA:RGD. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl. DR GO; GO:0043025; C:neuronal cell body; IDA:RGD. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0035356; P:cellular triglyceride homeostasis; IDA:RGD. DR GO; GO:0048839; P:inner ear development; IEP:RGD. DR GO; GO:0043066; P:negative regulation of apoptotic process; IDA:RGD. DR GO; GO:0051562; P:negative regulation of mitochondrial calcium ion concentration; IMP:RGD. DR GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; IDA:RGD. DR GO; GO:0070997; P:neuron death; IMP:RGD. DR GO; GO:0008284; P:positive regulation of cell proliferation; IDA:RGD. DR GO; GO:0046324; P:regulation of glucose import; IDA:RGD. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR Gene3D; 1.50.40.10; -; 1. DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier. DR InterPro; IPR023395; Mt_carrier_dom. DR Pfam; PF00153; Mito_carr; 3. DR SUPFAM; SSF103506; SSF103506; 1. DR PROSITE; PS50920; SOLCAR; 3. PE 2: Evidence at transcript level; KW Complete proteome {ECO:0000313|Proteomes:UP000002494}; KW Membrane {ECO:0000256|SAAS:SAAS00423863}; KW Reference proteome {ECO:0000313|Proteomes:UP000002494}; KW Transmembrane {ECO:0000256|RuleBase:RU000488, KW ECO:0000256|SAAS:SAAS00423777}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00423880}; KW Transport {ECO:0000256|RuleBase:RU000488}. SQ SEQUENCE 275 AA; 30536 MW; 118AE780E40219F1 CRC64; MQGEAALAKL GDGAMESAPY RGMMRTALGI VQEEGFLKLW QGVTPAIYRH VVYSGGRMVT YEHLREVVFG KSEDEHYPLW KSVIGGMMAG VIGQFLANPT DLVKVQMQME GKRRLEGKPL RFRGVHHAFA KILAEGGIRG LWAGWIPNIQ RAALVNMGDL TTYDTVKHYL VLNTALEDNI ATHGLSSLCS GLVASILGTP ADVIKSRIMN QPRDKQGRGL LYKSSTDCVI QAVQGEGFLS LYKGFLPSWL RMTPWSMVFW LTYEKIRQLS GVSPF //