ID Q6PEB5_MOUSE Unreviewed; 338 AA. AC Q6PEB5; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 13-NOV-2019, entry version 130. DE SubName: Full=H2-Bl protein {ECO:0000313|EMBL:AAH58170.1}; DE SubName: Full=Truncated MHC class I antigen splice variant Bl.1a {ECO:0000313|EMBL:AAY51868.1}; GN Name=H2-Bl {ECO:0000313|EMBL:AAH58170.1, ECO:0000313|MGI:MGI:892004}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH58170.1}; RN [1] {ECO:0000313|EMBL:AAH58170.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Mix FVB/N {ECO:0000313|EMBL:AAH58170.1}; RC TISSUE=Mammary tumor. WAP-TGF alpha model. 7 months old RC {ECO:0000313|EMBL:AAH58170.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [2] {ECO:0000313|EMBL:AAY51868.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=CD1 {ECO:0000313|EMBL:AAY51868.1}, and FVB/NJ RC {ECO:0000313|EMBL:AAY51869.1}; RC TISSUE=Small intestine {ECO:0000313|EMBL:AAY51868.1}; RX PubMed=16210630; RA Guidry P.A., Stroynowski I.; RT "The murine family of gut-restricted class Ib MHC includes RT alternatively spliced isoforms of the proposed HLA-G homolog, RT "blastocyst MHC"."; RL J. Immunol. 175:5248-5259(2005). CC -!- SIMILARITY: Belongs to the MHC class I family. CC {ECO:0000256|RuleBase:RU004439}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC058170; AAH58170.1; -; mRNA. DR EMBL; AY989853; AAY51868.1; -; mRNA. DR EMBL; AY989854; AAY51869.1; -; mRNA. DR PRIDE; Q6PEB5; -. DR MGI; MGI:892004; H2-Bl. DR ChiTaRS; H2-Bl; mouse. DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central. DR GO; GO:0005615; C:extracellular space; IBA:GO_Central. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central. DR GO; GO:0002476; P:antigen processing and presentation of endogenous peptide antigen via MHC class Ib; IBA:GO_Central. DR Gene3D; 2.60.40.10; -; 1. DR Gene3D; 3.30.500.10; -; 1. DR InterPro; IPR007110; Ig-like_dom. DR InterPro; IPR036179; Ig-like_dom_sf. DR InterPro; IPR013783; Ig-like_fold. DR InterPro; IPR003006; Ig/MHC_CS. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR011161; MHC_I-like_Ag-recog. DR InterPro; IPR037055; MHC_I-like_Ag-recog_sf. DR InterPro; IPR011162; MHC_I/II-like_Ag-recog. DR InterPro; IPR001039; MHC_I_a_a1/a2. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF00129; MHC_I; 1. DR PRINTS; PR01638; MHCCLASSI. DR SMART; SM00407; IGc1; 1. DR SUPFAM; SSF48726; SSF48726; 1. DR SUPFAM; SSF54452; SSF54452; 1. DR PROSITE; PS50835; IG_LIKE; 1. DR PROSITE; PS00290; IG_MHC; 1. PE 2: Evidence at transcript level; KW Disulfide bond {ECO:0000256|SAAS:SAAS00299355}; KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT SIGNAL 1 21 {ECO:0000256|SAM:SignalP}. FT CHAIN 22 338 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5014310596. FT TRANSMEM 297 317 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 195 283 Ig-like. {ECO:0000259|PROSITE:PS50835}. FT REGION 47 66 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. SQ SEQUENCE 338 AA; 38077 MW; AA892E687FCF61C0 CRC64; MAQRTLLLLL AAALTMIQTR AVFGPGLGEP RFISVGYVDN TQFVSFDSDA ENPRSEPRSP WMEQEGPEYW ERETQIAKDN EQSFGWSLRN LIHYYNQSKG GFHTFQRLSG CDMGLDGRLL RGYLQFAYDG RDYIALNEDL KTWMAADLVA LITRRKWEQA GAAELYKFYL EGECVEWLRR YLELGNETLL RTDPPKAHVT RHPRPAGDVT LRCWALGFYP ADITLTWQLN GEELTQDMEL VETRPAGDGT FQKWAAVVVP LGKEQNYTCR VHHEGLPEPL TLRWEPPPST GSNMVNIAVL VVLGAVIIIE AMVAFALKSR RKIAILPGPA GTRGSSAS //