ID Q6PCM9_MOUSE PRELIMINARY; PRT; 529 AA. AC Q6PCM9; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 11-JUL-2006, entry version 18. DE Notch2 protein. GN Name=Notch2; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6; TISSUE=Brain; RG NIH MGC Project; RL Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC059256; AAH59256.1; -; mRNA. DR SMR; Q6PCM9; 13-128. DR Ensembl; ENSMUSG00000027878; Mus musculus. DR MGI; MGI:97364; Notch2. DR GO; GO:0005615; C:extracellular space; RCA. DR GO; GO:0016021; C:integral to membrane; RCA. DR GO; GO:0003700; F:transcription factor activity; RCA. DR GO; GO:0007368; P:determination of left/right symmetry; IMP. DR GO; GO:0030326; P:embryonic limb morphogenesis; IGI. DR GO; GO:0002011; P:morphogenesis of an epithelial sheet; IMP. DR GO; GO:0043065; P:positive regulation of apoptosis; IGI. DR InterPro; IPR002110; ANK. DR Pfam; PF00023; Ank; 3. DR PRINTS; PR01415; ANKYRIN. DR SMART; SM00248; ANK; 2. DR PROSITE; PS50297; ANK_REP_REGION; 1. DR PROSITE; PS50088; ANK_REPEAT; 2. KW ANK repeat; Repeat. SQ SEQUENCE 529 AA; 56426 MW; C26EAAB89E68A966 CRC64; MYGKVDSVRG RNLEGMVAEL INCQADVNAV DDHGKSALHW AAAVNNVEAT FLLLKNGANR DMQDNKEETP LFLAAREGSY EAAKILLDHF ANRDITDHMD RLPRDVARDR MHHDIVRLLD EYNVTPSPPG TVLTSALSPV LCGPNRSFLS LKHTPMGKKA RRPNTKSTMP TSLPNLAKEA KDAKGSRRKK CLNEKVQLSE SSVTLSPVDS LESPHTYVSD ATSSPMITSP GILQASPTPL LAAAAPAAPV HTQHALSFSN LHDMQPLAPG ASTVLPSVSQ LLSHHHIAPP GSSSAGSLGR LHPVPVPADW MNRVEMNETQ YSEMFGMVLA PAEGAHPGIA APQSRPPEGK HMSTQREPLP PIVTFQLIPK GSIAQAAGAP QTQSSCPPAV AGPLPSMYQI PEMPRLPSVA FPPTMMPQQE GQVAQTIVPT YHPFPASVGK YPTPPSQHSY ASSNAAERTP SHGGHLQGEH PYLTPSPESP DQWSSSSPHS ASDWSDVTTS PTPGGGGGGQ RGPGTHMSEP PHSNMQVYA //