ID Q6P9M2_MOUSE Unreviewed; 906 AA. AC Q6P9M2; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 06-JUL-2016, entry version 96. DE SubName: Full=Gria1 protein {ECO:0000313|EMBL:AAH60702.1}; DE Flags: Fragment; GN Name=Gria1 {ECO:0000313|EMBL:AAH60702.1, ECO:0000313|MGI:MGI:95808}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH60702.1}; RN [1] {ECO:0000313|EMBL:AAH60702.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6 {ECO:0000313|EMBL:AAH60702.1}; RC TISSUE=Brain {ECO:0000313|EMBL:AAH60702.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell CC membrane {ECO:0000256|SAAS:SAAS00544997}. CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC CC 1.A.10.1) family. {ECO:0000256|SAAS:SAAS00542979}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC060702; AAH60702.1; -; mRNA. DR UniGene; Mm.4920; -. DR ProteinModelPortal; Q6P9M2; -. DR STRING; 10090.ENSMUSP00000044494; -. DR PaxDb; Q6P9M2; -. DR PeptideAtlas; Q6P9M2; -. DR MGI; MGI:95808; Gria1. DR eggNOG; KOG1054; Eukaryota. DR eggNOG; ENOG410XPSH; LUCA. DR HOVERGEN; HBG051839; -. DR ChiTaRS; Gria1; mouse. DR Bgee; Q6P9M2; -. DR Genevisible; Q6P9M2; MM. DR GO; GO:0030054; C:cell junction; IEA:UniProtKB-KW. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. DR GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro. DR GO; GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro. DR InterPro; IPR001828; ANF_lig-bd_rcpt. DR InterPro; IPR019594; Glu/Gly-bd. DR InterPro; IPR001508; Iono_rcpt_met. DR InterPro; IPR001320; Iontro_rcpt. DR InterPro; IPR028082; Peripla_BP_I. DR Pfam; PF01094; ANF_receptor; 1. DR Pfam; PF00060; Lig_chan; 1. DR Pfam; PF10613; Lig_chan-Glu_bd; 1. DR PRINTS; PR00177; NMDARECEPTOR. DR SMART; SM00918; Lig_chan-Glu_bd; 1. DR SMART; SM00079; PBPe; 1. DR SUPFAM; SSF53822; SSF53822; 1. PE 2: Evidence at transcript level; KW Cell junction {ECO:0000256|SAAS:SAAS00120395}; KW Cell membrane {ECO:0000256|SAAS:SAAS00120334}; KW Ion channel {ECO:0000256|SAAS:SAAS00543458}; KW Ion transport {ECO:0000256|SAAS:SAAS00543687}; KW Ligand-gated ion channel {ECO:0000256|SAAS:SAAS00542854}; KW Membrane {ECO:0000256|SAAS:SAAS00425055, ECO:0000256|SAM:Phobius}; KW Postsynaptic cell membrane {ECO:0000256|SAAS:SAAS00120352}; KW Receptor {ECO:0000256|SAAS:SAAS00428369}; KW Signal {ECO:0000256|SAM:SignalP}; KW Synapse {ECO:0000256|SAAS:SAAS00120443}; KW Transmembrane {ECO:0000256|SAAS:SAAS00425026, KW ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAAS:SAAS00425515, KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00586666}. FT SIGNAL 1 17 {ECO:0000256|SAM:SignalP}. FT CHAIN 18 906 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5004277838. FT TRANSMEM 534 556 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 617 639 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 807 829 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 407 782 PBPe. {ECO:0000259|SMART:SM00079}. FT DOMAIN 417 482 Lig_chan-Glu_bd. {ECO:0000259|SMART: FT SM00918}. FT NON_TER 1 1 {ECO:0000313|EMBL:AAH60702.1}. SQ SEQUENCE 906 AA; 101462 MW; 91B98C386FA85C99 CRC64; PYIFAFFCTG FLGAVVGANF PNNIQIGGLF PNQQSQEHAA FRFALSQLTE PPKLLPQIDI VNISDSFEMT YRFCSQFSKG VYAIFGFYER RTVNMLTSFC GALHVCFITP SFPVDTSNQF VLQLRPELQE ALISIIDHYK WQTFVYIYDA DRGLSVLQRV LDTAAEKNWQ VTAVNILTTT EEGYRMLFQD LEKKKERLVV VDCESERLNA ILGQIVKLEK NGIGYHYILA NLGFMDIDLN KFKESGANVT GFQLVNYTDT IPARIMQQWR TSDARDHTRV DWKRPKYTSA LTYDGVKVMA EAFQSLRRQR IDISRRGNAG DCLANPAVPW GQGIDIQRAL QQVRFEGLTG NVQFNEKGRR TNYTLHVIEM KHDGIRKIGY WNEDDKFVPA ATDAQAGGDN SSVQNRTYIV TTILEDPYVM LKKNANQFEG NDRYEGYCVE LAAEIAKHVG YSYRLEIVSD GKYGARDPDT KAWNGMVGEL VYGRADVAVA PLTITLVREE VIDFSKPFMS LGISIMIKKP QKSKPGVFSF LDPLAYEIWM CIVFAYIGVS VVLFLVSRFS PYEWHSEEFE EGRDQTTSDQ SNEFGIFNSL WFSLGAFMQQ GCDISPRSLS GRIVGGVWWF FTLIIISSYT ANLAAFLTVE RMVSPIESAE DLAKQTEIAY GTLEAGSTKE FFRRSKIAVF EKMWTYMKSA EPSVFVRTTE EGMIRVRKSK GKYAYLLEST MNEYIEQRKP CDTMKVGGNL DSKGYGIATP KGSALRNPVN LAVLKLNEQG LLDKLKNKWW YDKGECGSGG GDSKDKTSAL SLSNVAGVFY ILIGGLGLAM LVALIEFCYK SRSESKRMKG FCLIPQQSIN EAIRTSTLPR NSGAGASGGS GSGENGRVVS QDFPKSMQSI PCMSHSSGMP LGATGL //