ID Q6NZ93_HUMAN Unreviewed; 153 AA. AC Q6NZ93; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 03-MAR-2009, entry version 36. DE SubName: Full=Interleukin 2; GN Name=IL2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=PCR rescued clones; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC066254; AAH66254.1; -; mRNA. DR IPI; IPI00003099; -. DR UniGene; Hs.89679; -. DR SMR; Q6NZ93; 25-153. DR Ensembl; ENSG00000109471; Homo sapiens. DR HGNC; HGNC:6001; IL2. DR HOVERGEN; Q6NZ93; -. DR ArrayExpress; Q6NZ93; -. DR Bgee; Q6NZ93; -. DR GO; GO:0005615; C:extracellular space; IEA:Compara. DR GO; GO:0005125; F:cytokine activity; IEA:Compara. DR GO; GO:0005134; F:interleukin-2 receptor binding; IEA:InterPro. DR GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Compara. DR GO; GO:0050672; P:negative regulation of lymphocyte prolifera...; IEA:Compara. DR GO; GO:0042104; P:positive regulation of activated T cell pro...; IEA:Compara. DR GO; GO:0051024; P:positive regulation of immunoglobulin secre...; IEA:Compara. DR GO; GO:0048304; P:positive regulation of isotype switching to...; IEA:Compara. DR GO; GO:0045944; P:positive regulation of transcription from R...; IEA:Compara. DR GO; GO:0042523; P:positive regulation of tyrosine phosphoryla...; IEA:Compara. DR GO; GO:0046013; P:regulation of T cell homeostatic proliferation; IEA:Compara. DR InterPro; IPR012351; 4_helix_cytokine_core. DR InterPro; IPR000779; Interleukin-2. DR Gene3D; G3DSA:1.20.1250.10; 4_helix_cytokine_core; 1. DR PANTHER; PTHR11443; Interleukin-2; 1. DR Pfam; PF00715; IL2; 1. DR PRINTS; PR00265; INTERLEUKIN2. DR ProDom; PD003649; Interleukin-2; 1. DR SMART; SM00189; IL2; 1. DR PROSITE; PS00424; INTERLEUKIN_2; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 153 AA; 17598 MW; 1942F50F25960E88 CRC64; MYRMQLLSCI ALSLALVANS APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT //