ID CDPF1_HUMAN Reviewed; 123 AA. AC Q6NVV7; A6NCA1; A9IU12; A9IU16; Q3ZCR8; DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2004, sequence version 1. DT 06-JUL-2016, entry version 94. DE RecName: Full=Cysteine-rich DPF motif domain-containing protein 1; GN Name=CDPF1; Synonyms=C22orf40; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=10591208; DOI=10.1038/990031; RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., RA Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., RA Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., RA Bird C.P., Blakey S.E., Bridgeman A.M., Buck D., Burgess J., RA Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., RA Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., RA Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., RA Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., RA Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., RA Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., RA Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., RA Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., RA Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., RA Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., RA Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., RA Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., RA Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., RA Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., RA Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., RA Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., RA Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., RA Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., RA Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., RA Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., RA Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., RA Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., RA Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., RA Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., RA Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., RA Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., RA Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., RA Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., RA Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., RA O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., RA Khan A.S., Lane L., Tilahun Y., Wright H.; RT "The DNA sequence of human chromosome 22."; RL Nature 402:489-495(1999). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., RA Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Brain, and Placenta; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- INTERACTION: CC O14503:BHLHE40; NbExp=3; IntAct=EBI-2802782, EBI-711810; CC -!- SIMILARITY: Belongs to the CDPF1 family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL078611; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CH471138; EAW73407.1; -; Genomic_DNA. DR EMBL; BC045796; AAH45796.1; -; mRNA. DR EMBL; BC067871; AAH67871.1; -; mRNA. DR CCDS; CCDS33670.1; -. DR RefSeq; NP_997210.3; NM_207327.4. DR RefSeq; XP_011528267.1; XM_011529965.1. DR UniGene; Hs.103110; -. DR UniGene; Hs.592209; -. DR ProteinModelPortal; Q6NVV7; -. DR BioGrid; 127293; 3. DR IntAct; Q6NVV7; 2. DR iPTMnet; Q6NVV7; -. DR PhosphoSite; Q6NVV7; -. DR BioMuta; CDPF1; -. DR DMDM; 74749009; -. DR EPD; Q6NVV7; -. DR MaxQB; Q6NVV7; -. DR PaxDb; Q6NVV7; -. DR PeptideAtlas; Q6NVV7; -. DR PRIDE; Q6NVV7; -. DR DNASU; 150383; -. DR Ensembl; ENST00000314567; ENSP00000325301; ENSG00000205643. DR GeneID; 150383; -. DR KEGG; hsa:150383; -. DR UCSC; uc003bhe.4; human. DR CTD; 150383; -. DR GeneCards; CDPF1; -. DR HGNC; HGNC:33710; CDPF1. DR HPA; HPA018823; -. DR neXtProt; NX_Q6NVV7; -. DR PharmGKB; PA162379006; -. DR eggNOG; KOG4543; Eukaryota. DR eggNOG; ENOG4111ZD4; LUCA. DR GeneTree; ENSGT00390000007925; -. DR HOGENOM; HOG000006647; -. DR HOVERGEN; HBG098217; -. DR InParanoid; Q6NVV7; -. DR OMA; PCVRENI; -. DR PhylomeDB; Q6NVV7; -. DR TreeFam; TF313933; -. DR GenomeRNAi; 150383; -. DR PRO; PR:Q6NVV7; -. DR Proteomes; UP000005640; Chromosome 22. DR Bgee; Q6NVV7; -. DR CleanEx; HS_C22orf40; -. DR ExpressionAtlas; Q6NVV7; baseline and differential. DR Genevisible; Q6NVV7; HS. DR InterPro; IPR018785; Cys-rich_DPF. DR Pfam; PF10170; C6_DPF; 1. DR PRINTS; PR01995; UPF0595. PE 1: Evidence at protein level; KW Complete proteome; Polymorphism; Reference proteome. FT CHAIN 1 123 Cysteine-rich DPF motif domain-containing FT protein 1. FT /FTId=PRO_0000341360. FT VARIANT 5 5 V -> A (in dbSNP:rs9627281). FT /FTId=VAR_044058. FT VARIANT 70 70 L -> R (in dbSNP:rs55641018). FT /FTId=VAR_062237. FT CONFLICT 103 103 Q -> R (in Ref. 3; AAH45796). FT {ECO:0000305}. SQ SEQUENCE 123 AA; 13877 MW; 87E30A594058235F CRC64; MASHVECRPL GVFECELCTL TAPYSYVGQK PPNTQSMVLL EESYVMKDPF TSDKDRFLVL GSCCSLCSRL VCVGPECSLF YSKRFCLPCV RENINAFPQE IRQDLEKRKA PSKRTPSQPG SRT //