ID CV040_HUMAN Reviewed; 123 AA. AC Q6NVV7; A6NCA1; A9IU12; A9IU16; Q3ZCR8; DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2004, sequence version 1. DT 08-FEB-2011, entry version 58. DE RecName: Full=UPF0595 protein C22orf40; GN Name=C22orf40; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX MEDLINE=20057165; PubMed=10591208; DOI=10.1038/990031; RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., RA Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., RA Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., RA Bird C.P., Blakey S.E., Bridgeman A.M., Buck D., Burgess J., RA Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., RA Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., RA Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., RA Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., RA Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., RA Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., RA Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., RA Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., RA Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., RA Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., RA Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., RA Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., RA Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., RA Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., RA Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., RA Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., RA Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., RA Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., RA Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., RA Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., RA Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., RA Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., RA Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., RA Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., RA Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., RA Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., RA Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., RA Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., RA Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., RA O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., RA Khan A.S., Lane L., Tilahun Y., Wright H.; RT "The DNA sequence of human chromosome 22."; RL Nature 402:489-495(1999). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., RA Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Brain, and Placenta; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SIMILARITY: Belongs to the UPF0595 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL078611; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; CH471138; EAW73407.1; -; Genomic_DNA. DR EMBL; BC045796; AAH45796.1; -; mRNA. DR EMBL; BC067871; AAH67871.1; -; mRNA. DR IPI; IPI00086860; -. DR RefSeq; NP_997210.3; NM_207327.4. DR UniGene; Hs.103110; -. DR UniGene; Hs.592209; -. DR ProteinModelPortal; Q6NVV7; -. DR IntAct; Q6NVV7; 1. DR PRIDE; Q6NVV7; -. DR Ensembl; ENST00000314567; ENSP00000325301; ENSG00000205643. DR GeneID; 150383; -. DR KEGG; hsa:150383; -. DR UCSC; uc003bhe.1; human. DR CTD; 150383; -. DR GeneCards; GC22M046640; -. DR HGNC; HGNC:33710; C22orf40. DR HPA; HPA018823; -. DR neXtProt; NX_Q6NVV7; -. DR PharmGKB; PA162379006; -. DR eggNOG; prNOG20702; -. DR GeneTree; ENSGT00500000045835; -. DR HOVERGEN; HBG098217; -. DR OMA; SAFPQEI; -. DR NextBio; 86438; -. DR ArrayExpress; Q6NVV7; -. DR Bgee; Q6NVV7; -. DR CleanEx; HS_C22orf40; -. DR Genevestigator; Q6NVV7; -. DR InterPro; IPR018785; Cys-rich_DPF. DR Pfam; PF10170; C6_DPF; 1. DR PRINTS; PR01995; UPF0595. PE 2: Evidence at transcript level; KW Complete proteome; Polymorphism. FT CHAIN 1 123 UPF0595 protein C22orf40. FT /FTId=PRO_0000341360. FT VARIANT 5 5 V -> A (in dbSNP:rs9627281). FT /FTId=VAR_044058. FT VARIANT 70 70 L -> R (in dbSNP:rs55641018). FT /FTId=VAR_062237. FT CONFLICT 103 103 Q -> R (in Ref. 3; AAH45796). SQ SEQUENCE 123 AA; 13877 MW; 87E30A594058235F CRC64; MASHVECRPL GVFECELCTL TAPYSYVGQK PPNTQSMVLL EESYVMKDPF TSDKDRFLVL GSCCSLCSRL VCVGPECSLF YSKRFCLPCV RENINAFPQE IRQDLEKRKA PSKRTPSQPG SRT //