ID Q6NNU5_DROME Unreviewed; 1034 AA. AC Q6NNU5; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 17-JUN-2020, entry version 79. DE RecName: Full=AP-3 complex subunit delta {ECO:0000256|PIRNR:PIRNR037092}; GN Name=g {ECO:0000313|EMBL:AAR88549.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAR88549.1}; RN [1] {ECO:0000313|EMBL:AAR88549.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley {ECO:0000313|EMBL:AAR88549.1}; RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., RA Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., RA Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A., RA Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., RA Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.; RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. CC -!- SUBUNIT: Adaptor protein complex 3 (AP-3) is a heterotetramer. CC {ECO:0000256|PIRNR:PIRNR037092}. CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092}. CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family. CC {ECO:0000256|PIRNR:PIRNR037092}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BT011188; AAR88549.1; -; mRNA. DR PRIDE; Q6NNU5; -. DR eggNOG; KOG1059; Eukaryota. DR eggNOG; ENOG410XQFB; LUCA. DR HOGENOM; CLU_001908_0_1_1; -. DR ChiTaRS; g; fly. DR Bgee; FBgn0001087; Expressed in wing disc (Drosophila) and 31 other tissues. DR ExpressionAtlas; Q6NNU5; baseline and differential. DR GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro. DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro. DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro. DR Gene3D; 1.25.10.10; -; 1. DR InterPro; IPR017105; AP3_complex_dsu. DR InterPro; IPR011989; ARM-like. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N. DR PANTHER; PTHR22781; PTHR22781; 1. DR Pfam; PF01602; Adaptin_N; 1. DR PIRSF; PIRSF037092; AP3_complex_delta; 1. DR SUPFAM; SSF48371; SSF48371; 1. PE 2: Evidence at transcript level; KW Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092}; KW Membrane {ECO:0000256|SAAS:SAAS00468874}; KW Protein transport {ECO:0000256|PIRNR:PIRNR037092, KW ECO:0000256|SAAS:SAAS00299732}; KW Transport {ECO:0000256|PIRNR:PIRNR037092, ECO:0000256|SAAS:SAAS00468876}. FT DOMAIN 33..578 FT /note="Adaptin_N" FT /evidence="ECO:0000259|Pfam:PF01602" FT REGION 637..660 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 669..688 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 701..723 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 758..1034 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 768..784 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 815..840 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 874..909 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 921..941 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1034 AA; 114811 MW; AF24C4415611A1EA CRC64; MALKKVKGNF FERMFDKNLT DLVRGIRNNK DNEAKYISTC IEEIKQELRQ DNISVKCNAV AKLTYIQMLG YDISWAGFNI IEVMSSSRFT CKRIGYLAAS QCFHPDSELL MLTTNMIRKD LNSQNQYDAG VALSGLSCFI SPDLSRDLAN DIMTLMSSTK PYLRMKAVLM MYKVFLRYPE ALRPAFPKLK EKLEDPDPGV QSAAVNVICE LARKNPKNYL PLAPIFFKLM TTSTNNWMLI KIIKLFGALT PLEPRLGKKL IEPLTNLIHS TSAMSLLYEC INTVIAVLIS ISSGMPNHSA SIQLCVQKLR ILIEDSDQNL KYLGLLAMSK ILKTHPKSVQ AHKDLILACL DDEDESIRLR ALDLLYGMVS KKNLMEIVKR LLGHMERAEG SAYRDELLYK VIEICAQSSY LYVTNFEWYL TVLVELIQLE AGSRHGRLIA EQLLDVAIRV PVVRQFAVNE MTNLLDTFTV SAQSNSMYEV LYAAAWIVGE FAGELEDAEK TLNILLRPRL LPGHIQGVYV QNVIKLFARL ATTCLELQDL PGLVTLCDHV LDKLQHFNGS SDIEVQERAN SACMLIEMLR NQLSTSTDAM AMDTTTEGGI PPLAIEIVQE MTLLFTGELI PVAPKAQRKV PLPDGLDLDE WINAPPPEDA ASSSSSEHDK DELFVSATQA GTGADGGEKR RQSLELTPEQ LERQRMARLI EQSNNPHYLK STPTASGASN ADQYDNIDDI PITELPLDME GVAALRVGIT KRSDKYLQEQ QAAQGSKDGK KKHKKGKKSK KAKNKVAYNS SSESEGEPKP LHIVNTTLDM PEGVSMSDSE DKDGKYDPND PHRALDIELD ITEFEAPAVR SASKKSAADK ENLKTPADSA GGGNAAKKDR KKDKDKDKER KVKREHRESK RERKEAAVQS VIDLIDADTP TPSPSHISAT SNNNNTSTVL PDAPKHHKKK KNKEKTTDEA PDALATATGS SIIDVGGEEA SEVASKVHKK KHKKEKSQRK EKKKASESAS VSAIVSIGDY EQPLGISTPS KEIL //