ID Q6MTI5 PRELIMINARY; PRT; 447 AA. AC Q6MTI5; DT 05-JUL-2004 (TrEMBLrel. 27, Created) DT 05-JUL-2004 (TrEMBLrel. 27, Last sequence update) DT 05-JUL-2004 (TrEMBLrel. 27, Last annotation update) DE Signal recognition particle M54 protein. GN Name=ffh; OrderedLocusNames=MSC_0423; OS Mycoplasma mycoides (subsp. mycoides SC). OC Bacteria; Firmicutes; Mollicutes; Mycoplasmataceae; Mycoplasma. OX NCBI_TaxID=44101; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=PG1; RX PubMed=14762060; DOI=10.1101/gr.1673304; RA Westberg J., Persson A., Holmberg A., Goesmann A., Lundeberg J., RA Johansson K.-E., Pettersson B., Uhlen M.; RT "The genome sequence of Mycoplasma mycoides subsp. mycoides SC type RT strain PG1T, the causative agent of contagious bovine pleuropneumonia RT (CBPP)."; RL Genome Res. 14:221-227(2004). CC -!- FUNCTION: Necessary for efficient export of extra-cytoplasmic CC proteins. Binds to the signal sequence when it emerges from the CC ribosomes (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity). CC -!- DOMAIN: Has a two domain structure: the G-domain binds GTP; the M- CC domain binds the 7S RNA in presence of SRP19 and also binds the CC signal sequence (By similarity). CC -!- DOMAIN: The protein has a two domain structure: the G-domain binds CC GTP; the M-domain binds the RNA and also binds the signal sequence CC (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX842643; CAE77051.1; -. DR GO; GO:0005786; C:signal recognition particle (sensu Eukaryota); IEA. DR GO; GO:0005525; F:GTP binding; IEA. DR GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA. DR GO; GO:0000166; F:nucleotide binding; IEA. DR GO; GO:0003723; F:RNA binding; IEA. DR GO; GO:0006605; P:protein targeting; IEA. DR GO; GO:0006614; P:SRP-dependent cotranslational protein-membr...; IEA. DR InterPro; IPR003593; AAA_ATPase. DR InterPro; IPR000897; SRP54. DR InterPro; IPR004125; SRP54_SPB. DR InterPro; IPR004780; SRP_sub. DR Pfam; PF00448; SRP54; 1. DR Pfam; PF02881; SRP54_N; 1. DR Pfam; PF02978; SRP_SPB; 1. DR ProDom; PD000819; SRP54; 1. DR SMART; SM00382; AAA; 1. DR TIGRFAMs; TIGR00959; ffh; 1. DR PROSITE; PS00300; SRP54; 1. KW Complete proteome; GTP-binding; RNA-binding; KW Signal recognition particle. SQ SEQUENCE 447 AA; 50160 MW; D27FE990C7FDD479 CRC64; MGFGDFLSKR MQKSIEKNMK NSTLNEENIK ETLKEIRLSL LEADVNIEAT KEIINNVKQK ALGGYIFEGA NAHQQMIKIV HEELVNILGK ENAPLELNKK PSVVMMVGLQ GSGKTTTANK LAYLLNKKNK KKVLLVGLDI YRPGAIEQLI QLGQKTNIQV FEKGKQDPIL TAQEALEYAQ ENNFDVVILD TAGRLQVDQV LMTELDNLKK KTSPSEILLV VDGMSGQEII NVTNEFNSKL KLSGVVVTKL DGDARGGATL SISYLTKLPI KFIGEGEGYN ALAAFYPKRM ADRLMGMGDI ETLFEKAVEN IDERSIQKTM NRMFLGQFDL EDLRNQLAQI AKMGSLNKLM KMLPINKVSE TQIQDAQRKL AVFSILMDSM TLKERRDPRV LKAISRKNRI IKGSGRTEKE FNELINSFEK GKKQVLEITK MIKSGRMPNL SKGGFKF //