ID Q6LA97_HUMAN Unreviewed; 79 AA. AC Q6LA97; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 03-OCT-2012, entry version 40. DE SubName: Full=Apolipoprotein E; DE Flags: Fragment; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Brain; RA Dmitrenko V.V., Garifulin O.M., Kavsan V.M.; RT "Characterization of different mRNA types expressed in human brain."; RL Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z70760; CAA94806.1; -; mRNA. DR IPI; IPI00879368; -. DR UniGene; Hs.654439; -. DR HSSP; P02649; 1B68. DR STRING; Q6LA97; -. DR PRIDE; Q6LA97; -. DR HOGENOM; HOG000034006; -. DR ArrayExpress; Q6LA97; -. DR Bgee; Q6LA97; -. DR GO; GO:0030425; C:dendrite; IEA:Compara. DR GO; GO:0005769; C:early endosome; IEA:Compara. DR GO; GO:0005615; C:extracellular space; IEA:Compara. DR GO; GO:0031232; C:extrinsic to external side of plasma membrane; IEA:Compara. DR GO; GO:0005794; C:Golgi apparatus; IEA:Compara. DR GO; GO:0005770; C:late endosome; IEA:Compara. DR GO; GO:0005874; C:microtubule; IEA:Compara. DR GO; GO:0043025; C:neuronal cell body; IEA:Compara. DR GO; GO:0017127; F:cholesterol transporter activity; IEA:Compara. DR GO; GO:0071813; F:lipoprotein particle binding; IEA:Compara. DR GO; GO:0005543; F:phospholipid binding; IEA:Compara. DR GO; GO:0007568; P:aging; IEA:Compara. DR GO; GO:0048844; P:artery morphogenesis; IEA:Compara. DR GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Compara. DR GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Compara. DR GO; GO:0006707; P:cholesterol catabolic process; IEA:Compara. DR GO; GO:0033344; P:cholesterol efflux; IEA:Compara. DR GO; GO:0042632; P:cholesterol homeostasis; IEA:Compara. DR GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Compara. DR GO; GO:0042159; P:lipoprotein catabolic process; IEA:Compara. DR GO; GO:0034374; P:low-density lipoprotein particle remodeling; IEA:Compara. DR GO; GO:0051651; P:maintenance of location in cell; IEA:Compara. DR GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Compara. DR GO; GO:0014012; P:peripheral nervous system axon regeneration; IEA:Compara. DR GO; GO:0010468; P:regulation of gene expression; IEA:Compara. DR GO; GO:0002021; P:response to dietary excess; IEA:Compara. DR GO; GO:0045471; P:response to ethanol; IEA:Compara. DR GO; GO:0006979; P:response to oxidative stress; IEA:Compara. DR GO; GO:0042311; P:vasodilation; IEA:Compara. DR Gene3D; G3DSA:1.20.120.20; ApoA/E_ApoLp; 1. DR InterPro; IPR013326; ApoA/E_ApoLp. PE 2: Evidence at transcript level; KW Lipoprotein. FT NON_TER 79 79 SQ SEQUENCE 79 AA; 9321 MW; 4CF5C381045A39AC CRC64; MKVLWAALLV TFLAGCQAKV EQAVETEPEP ELRQQTEWQS GQRWELALGR FWDYLRWVQT LSEQVQEELL SSQVTQELR //