ID RECA_LACPE Reviewed; 378 AA. AC Q6KCK3; DT 27-SEP-2005, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2004, sequence version 1. DT 22-FEB-2023, entry version 79. DE RecName: Full=Protein RecA {ECO:0000255|HAMAP-Rule:MF_00268}; DE AltName: Full=Recombinase A {ECO:0000255|HAMAP-Rule:MF_00268}; GN Name=recA {ECO:0000255|HAMAP-Rule:MF_00268}; OS Lactiplantibacillus pentosus (Lactobacillus pentosus). OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; OC Lactiplantibacillus. OX NCBI_TaxID=1589; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 8041 / DSM 20314 / BCRC 11053 / JCM 1558 / KCTC 3120 / LMG RC 10755 / NBRC 106467 / NCDO 363 / NCIMB 8026 / 124-2; RX PubMed=16014493; DOI=10.1099/ijs.0.63333-0; RA Bringel F., Castioni A., Olukoya D.K., Felis G.E., Torriani S., RA Dellaglio F.; RT "Lactobacillus plantarum subsp. argentoratensis subsp. nov., isolated from RT vegetable matrices."; RL Int. J. Syst. Evol. Microbiol. 55:1629-1634(2005). CC -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single- CC stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex CC DNA, and the ATP-dependent hybridization of homologous single-stranded CC DNAs. It interacts with LexA causing its activation and leading to its CC autocatalytic cleavage. {ECO:0000255|HAMAP-Rule:MF_00268}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00268}. CC -!- SIMILARITY: Belongs to the RecA family. {ECO:0000255|HAMAP- CC Rule:MF_00268}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ621666; CAF21791.1; -; Genomic_DNA. DR RefSeq; WP_050339350.1; NZ_RDCL01000052.1. DR AlphaFoldDB; Q6KCK3; -. DR SMR; Q6KCK3; -. DR STRING; 1589.GCA_001188985_02308; -. DR GeneID; 49394474; -. DR OrthoDB; 9776733at2; -. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro. DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule. DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule. DR CDD; cd00983; recA; 1. DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1. DR HAMAP; MF_00268; RecA; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR013765; DNA_recomb/repair_RecA. DR InterPro; IPR020584; DNA_recomb/repair_RecA_CS. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR020588; RecA_ATP-bd. DR InterPro; IPR023400; RecA_C. DR InterPro; IPR020587; RecA_monomer-monomer_interface. DR PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1. DR PANTHER; PTHR45900; RECA; 1. DR Pfam; PF00154; RecA; 1. DR PRINTS; PR00142; RECA. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1. DR SUPFAM; SSF54752; RecA protein, C-terminal domain; 1. DR TIGRFAMs; TIGR02012; tigrfam_recA; 1. DR PROSITE; PS00321; RECA_1; 1. DR PROSITE; PS50162; RECA_2; 1. DR PROSITE; PS50163; RECA_3; 1. PE 3: Inferred from homology; KW ATP-binding; Cytoplasm; DNA damage; DNA recombination; DNA repair; KW DNA-binding; Nucleotide-binding; SOS response. FT CHAIN 1..378 FT /note="Protein RecA" FT /id="PRO_0000122735" FT REGION 325..378 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 325..355 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT BINDING 65..72 FT /ligand="ATP" FT /ligand_id="ChEBI:CHEBI:30616" FT /evidence="ECO:0000255|HAMAP-Rule:MF_00268" SQ SEQUENCE 378 AA; 40690 MW; 0CF98BB77F20ADCF CRC64; MADARKAALD TALKKIEKNF GKGAIMRMGD AAQTTISTIS SGSLALDDAL GVGGYPRGRI VEIYGPESSG KTTVALHAVA EVQKQGGTAA YIDAENALDP VYAEHLGVNI DDLLLSQPDT GEQGLEIADA LVSSGAVDIL VVDSVAALVP RAEIEGEMGD AHVGLQARLM SQALRKLSGT LNKTKTIALF INQIREKVGV MFGNPETTPG GRALKFYATI RLEVRRAEQI KEGTNIIGNR VRIKVVKNKV APPFKRAEVD IMYGQGISQT GEIVDMAAEK DIVKKSGSWY SYGDDRIGQG RENAKKYLDE HPDVMAEIRQ KVRDAYGMDQ TGEEDDQADD KSKDKATKPS DKSQAQAKPK KPVATETSLD LDDSKTDK //