ID Q6FHK9_HUMAN Unreviewed; 239 AA. AC Q6FHK9; DT 19-JUL-2004, integrated into UniProtKB/TrEMBL. DT 19-JUL-2004, sequence version 1. DT 02-JUN-2021, entry version 71. DE SubName: Full=PSME2 protein {ECO:0000313|EMBL:CAG46543.1}; GN Name=PSME2 {ECO:0000313|EMBL:CAG46543.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAG46543.1}; RN [1] {ECO:0000313|EMBL:CAG46543.1} RP NUCLEOTIDE SEQUENCE. RA Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., RA Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., RA LaBaer J.; RT "Cloning of human full open reading frames in Gateway(TM) system entry RT vector (pDONR201)."; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the PA28 family. CC {ECO:0000256|ARBA:ARBA00005883}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CR541743; CAG46543.1; -; mRNA. DR SMR; Q6FHK9; -. DR PeptideAtlas; Q6FHK9; -. DR OMA; STKVIKY; -. DR ChiTaRS; PSME2; human. DR GO; GO:0008537; C:proteasome activator complex; IEA:InterPro. DR Gene3D; 1.20.120.180; -; 1. DR Gene3D; 1.20.5.120; -; 1. DR InterPro; IPR003186; PA28_C. DR InterPro; IPR036997; PA28_C_sf. DR InterPro; IPR036996; PA28_N_sf. DR InterPro; IPR009077; Proteasome_activ_PA28. DR InterPro; IPR003185; Proteasome_activ_PA28_N. DR InterPro; IPR036252; Proteasome_activ_sf. DR PANTHER; PTHR10660; PTHR10660; 1. DR Pfam; PF02251; PA28_alpha; 1. DR Pfam; PF02252; PA28_beta; 1. DR SUPFAM; SSF47216; SSF47216; 1. PE 2: Evidence at transcript level; KW Proteasome {ECO:0000256|ARBA:ARBA00022942}. FT DOMAIN 12..71 FT /note="PA28_alpha" FT /evidence="ECO:0000259|Pfam:PF02251" FT DOMAIN 94..235 FT /note="PA28_beta" FT /evidence="ECO:0000259|Pfam:PF02252" FT REGION 65..86 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 70..86 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 239 AA; 27432 MW; 7E86145518EC739A CRC64; MAKPCGVRLS GEVRKQVEVF RQNLFQEAEE FLYRFLPQKI IYLNQLLQED SLNVADLTSL RAPLDIPIPD PPPKDDEMET DKQEKKEVPK CGFLPGNEKV LSLLALVKPE VWTLKEKCIL VITWIQHLIP KIEDGNDFGV AIQEKVLERV NAVKTKVEAF QTTISKYFSE RGDAVAKASK ETHVMDYRAL VHERDEAAYV ELRAMVLDLR AFYAELYHII SSNLEKIVNP KGEEKPSMY //