ID NUP85_XENTR Reviewed; 653 AA. AC Q6DK84; DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot. DT 16-AUG-2004, sequence version 1. DT 26-NOV-2014, entry version 59. DE RecName: Full=Nuclear pore complex protein Nup85; DE AltName: Full=85 kDa nucleoporin; DE AltName: Full=Nucleoporin Nup85; GN Name=nup85; OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; OC Silurana. OX NCBI_TaxID=8364; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Embryo; RG NIH - Xenopus Gene Collection (XGC) project; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Functions as component of the nuclear pore complex CC (NPC). {ECO:0000250}. CC -!- SUBUNIT: Component of the nuclear pore complex (NPC). CC {ECO:0000250}. CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex {ECO:0000250}. CC Nucleus membrane {ECO:0000250}. CC -!- SIMILARITY: Belongs to the nucleoporin Nup85 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC074592; AAH74592.1; -; mRNA. DR RefSeq; NP_001004817.1; NM_001004817.1. DR UniGene; Str.8414; -. DR STRING; 8364.ENSXETP00000056747; -. DR Ensembl; ENSXETT00000056747; ENSXETP00000056747; ENSXETG00000027060. DR GeneID; 448067; -. DR KEGG; xtr:448067; -. DR CTD; 79902; -. DR Xenbase; XB-GENE-1008050; nup85. DR eggNOG; NOG275863; -. DR GeneTree; ENSGT00390000000204; -. DR HOGENOM; HOG000230494; -. DR HOVERGEN; HBG059778; -. DR InParanoid; Q6DK84; -. DR KO; K14304; -. DR OMA; VVLAECS; -. DR OrthoDB; EOG76T9QP; -. DR TreeFam; TF323240; -. DR Reactome; REACT_207635; Separation of Sister Chromatids. DR Reactome; REACT_208808; Nuclear Pore Complex (NPC) Disassembly. DR Reactome; REACT_214596; Resolution of Sister Chromatid Cohesion. DR Reactome; REACT_220495; Regulation of Glucokinase by Glucokinase Regulatory Protein. DR Reactome; REACT_269204; Transcriptional regulation by small RNAs. DR Bgee; Q6DK84; -. DR GO; GO:0031080; C:nuclear pore outer ring; ISS:UniProtKB. DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW. DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW. DR InterPro; IPR011502; Nucleoporin_Nup85. DR Pfam; PF07575; Nucleopor_Nup85; 1. PE 2: Evidence at transcript level; KW Complete proteome; Membrane; mRNA transport; Nuclear pore complex; KW Nucleus; Protein transport; Reference proteome; Translocation; KW Transport. FT CHAIN 1 653 Nuclear pore complex protein Nup85. FT /FTId=PRO_0000324191. SQ SEQUENCE 653 AA; 74918 MW; FCF9A8F5C0EAAB1F CRC64; MEELDVDPAE TPIPGLGQQN RHIGFSWGPG DLLLYETLYQ KQGSETAARC PFMYLVRSDE DIYSPVLRKL FNESHSIFVG LQKSAEENAG KSRKAQLVQV SRNYRSVLRA CMEEMHALSE STREPSQNTK YISQISILSA MELSWNLCEI LFIESAPAGP LLILLLDWVR LHVCEVDNIV QDVLRSERPT EHEKFWDGVT GYVLQGRMNE ARQLLAKEAS SSVSARSMCR VLDDLLKKMP MLNTAGTQTL TEFELKWQHW REECERHLQN GTFSSNPHME VVCRVLVGDE EVILEKRDLM TTWYHFLVSR LLFKHPTVKP TELHFYAQSS LDMFLAGNSS PEPLDNILLA AFEFDIHQVI KEFSIVSSNW WFVAHLTDLL DHCQLFQAHN LYFGANMREF LLLDYASGLF SHHSLWQLGV DYFDYCPNLG HVYLELHMER VPLNTEKKAL KALRICEKRQ MTEQVRSICK TMAMQSLCNG RLGSALSWSI RAKDAAFATL ISDRFLKEYS ERGNFTDLDL IDNLGSAMLL SDRLTFLGKY REFHRMYSQE QFSEAASLLL SLMTARIAPC SFWLTLLLDA LPLLEQKQVI FSAEQTYELM RCLEDRMAAK LDSTSPDEIQ KQDSVDSTKI EMLRLALARN LARAIVTEGA LQE //