ID Q6DEG0_BRARE PRELIMINARY; PRT; 573 AA. AC Q6DEG0; DT 16-AUG-2004, integrated into UniProtKB/TrEMBL. DT 16-AUG-2004, sequence version 1. DT 07-FEB-2006, entry version 17. DE Zgc:92367. GN ORFNames=zgc:92367; OS Brachydanio rerio (Zebrafish) (Danio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Whole; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Whole; RA Director MGC Project; RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. CC -!- DOMAIN: The MATH/TRAF domain binds to receptor cytoplasmic domains CC (By similarity). CC -!- DOMAIN: The coiled coil domain mediates homo- and hetero- CC oligomerization (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC077157; AAH77157.1; -; mRNA. DR SMR; Q6DEG0; 386-573. DR Ensembl; ENSDARG00000022000; Danio rerio. DR ZFIN; ZDB-GENE-040801-257; zgc:92367. DR GO; GO:0000151; C:ubiquitin ligase complex; IEA. DR GO; GO:0046872; F:metal ion binding; IEA. DR GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA. DR GO; GO:0008270; F:zinc ion binding; IEA. DR GO; GO:0016567; P:protein ubiquitination; IEA. DR GO; GO:0042981; P:regulation of apoptosis; IEA. DR GO; GO:0007165; P:signal transduction; IEA. DR InterPro; IPR002083; MATH. DR InterPro; IPR013323; SIAH-type. DR InterPro; IPR012227; TRAF. DR InterPro; IPR013322; TRAF-type. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR001293; Znf_TRAF. DR Pfam; PF00917; MATH; 1. DR Pfam; PF02176; zf-TRAF; 2. DR PIRSF; PIRSF015614; TRAF; 1. DR SMART; SM00061; MATH; 1. DR SMART; SM00184; RING; 1. DR PROSITE; PS50144; MATH; 1. DR PROSITE; PS00518; ZF_RING_1; 1. DR PROSITE; PS50089; ZF_RING_2; 1. DR PROSITE; PS50145; ZF_TRAF; 2. KW Apoptosis; Coiled coil; Metal-binding; Zinc; Zinc-finger. SQ SEQUENCE 573 AA; 65608 MW; F7C441E6725833C2 CRC64; MSAGRNVEQQ IPLQQRPPSL AMPSMAQRPR PEPGFSPLHG GFRDHFVTTP EPKYCCETCR LVLCNPRQTE CGHRFCESCI NELLSKPNPV CPADLLPLFE DKIFRDVCCN REIMALKVYC RSEKNGCKEQ MCLQQVMEHL VICPYFEVPC PLGKCKEKMM RKDMPEHLSR KCKHREVTCE FCSLKMALTE LQKHKETVCP AFPVACPNHC SFSSILRSEL SSHQHDCPKA QVTCSFIRYG CSYKGLNQEM REHESSFASE HLRMMAVRNT TLEAKVEDVK SELMERYKVL PSLSSRLAEV ERQYEEMREK NRQLEQKLVS MQMLMSSHSE KLLEVEMELR ELRPLRAMRE EVETLRGSVE SMRSMVSSLD SSCVNSASGS HTLASLEQQL TRHDDLMSVH DVRLAEMDLK LQVLETASFN GTLIWKIRDY KRRKQEAVVS KTLSLYSQPF YTGYFGYKMC ARVYLNGDGM GKGTHLSLFF VVMRGEYDAL LQWPFKQKVT LMLMDQGPAR KHLGDAFKPD PSSSSFRRPT GEMNIASGCP LFVAQTVLEN GTYIKDDTIF IKVTVDTSDL PDP //