ID YTH1_DEBHA Reviewed; 223 AA. AC Q6BTT1; DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot. DT 16-DEC-2008, sequence version 2. DT 13-SEP-2023, entry version 92. DE RecName: Full=mRNA 3'-end-processing protein YTH1; GN Name=YTH1; OrderedLocusNames=DEHA2C16126g; OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Debaryomycetaceae; Debaryomyces. OX NCBI_TaxID=284592; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S., RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., RA Weissenbach J., Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Component of the cleavage factor I (CF I) involved in pre- CC mRNA 3'-end processing. {ECO:0000250}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. CC -!- SIMILARITY: Belongs to the CPSF4/YTH1 family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CR382135; CAG86470.2; -; Genomic_DNA. DR RefSeq; XP_458388.2; XM_458388.1. DR AlphaFoldDB; Q6BTT1; -. DR SMR; Q6BTT1; -. DR STRING; 4959.XP_458388.2; -. DR GeneID; 2900760; -. DR KEGG; dha:DEHA2C16126g; -. DR VEuPathDB; FungiDB:DEHA2C16126g; -. DR eggNOG; KOG1040; Eukaryota. DR HOGENOM; CLU_024513_1_2_1; -. DR InParanoid; Q6BTT1; -. DR OMA; SLVCKHY; -. DR OrthoDB; 33612at2759; -. DR Proteomes; UP000000599; Chromosome C. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. DR Gene3D; 3.30.1370.210; -; 1. DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1. DR InterPro; IPR045348; CPSF4/Yth1. DR InterPro; IPR000571; Znf_CCCH. DR InterPro; IPR036855; Znf_CCCH_sf. DR PANTHER; PTHR23102:SF24; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4; 1. DR PANTHER; PTHR23102; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED; 1. DR Pfam; PF14608; zf-CCCH_2; 4. DR SMART; SM00356; ZnF_C3H1; 5. DR SUPFAM; SSF90229; CCCH zinc finger; 2. DR PROSITE; PS50103; ZF_C3H1; 5. PE 3: Inferred from homology; KW Metal-binding; mRNA processing; Nucleus; Reference proteome; Repeat; KW RNA-binding; Zinc; Zinc-finger. FT CHAIN 1..223 FT /note="mRNA 3'-end-processing protein YTH1" FT /id="PRO_0000238537" FT ZN_FING 32..63 FT /note="C3H1-type 1" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723" FT ZN_FING 65..92 FT /note="C3H1-type 2" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723" FT ZN_FING 93..121 FT /note="C3H1-type 3" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723" FT ZN_FING 122..149 FT /note="C3H1-type 4" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723" FT ZN_FING 151..173 FT /note="C3H1-type 5" FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723" FT REGION 184..223 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 184..201 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 223 AA; 25709 MW; 0B668AC5D4EC15C6 CRC64; MLQLNQVIHP DTRNKRFKFE PFLLKEYNFG LDPDRPVCQF YNPSNPNNSC PNGSLCPHKH VSSMYSNKIV CKHWLRGLCK KNDHCEFLHE YNLRKMPECL FYSKNGFCTQ TPECLYLHVD PQSKIPPCSS YEKGFCPDGP KCANRHIRKI MCPLWLTGFC PKGAECDYTH PRFEAIIDRL RIKPDEDAVE EKEKVANGSD KEDQNMADAT SNGNTEEKDE SGP //