ID YTH1_DEBHA Reviewed; 223 AA. AC Q6BTT1; DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot. DT 16-DEC-2008, sequence version 2. DT 07-SEP-2016, entry version 62. DE RecName: Full=mRNA 3'-end-processing protein YTH1; GN Name=YTH1; OrderedLocusNames=DEHA2C16126g; OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC OS 0083 / IGC 2968) (Yeast) (Torulaspora hansenii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Debaryomyces. OX NCBI_TaxID=284592; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., RA Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., RA Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., RA Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., RA Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., RA Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., RA Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., RA Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., RA Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., RA Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., RA Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., RA Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., RA Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Component of the cleavage factor I (CF I) involved in CC pre-mRNA 3'-end processing. {ECO:0000250}. CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. CC -!- SIMILARITY: Belongs to the CPSF4/YTH1 family. {ECO:0000305}. CC -!- SIMILARITY: Contains 5 C3H1-type zinc fingers. CC {ECO:0000255|PROSITE-ProRule:PRU00723}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CR382135; CAG86470.2; -; Genomic_DNA. DR RefSeq; XP_458388.2; XM_458388.1. DR EnsemblFungi; CAG86470; CAG86470; DEHA2C16126g. DR GeneID; 2900760; -. DR KEGG; dha:DEHA2C16126g; -. DR HOGENOM; HOG000212457; -. DR InParanoid; Q6BTT1; -. DR KO; K14404; -. DR OMA; KMPECVF; -. DR OrthoDB; EOG092C59NU; -. DR Proteomes; UP000000599; Chromosome C. DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi. DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IEA:EnsemblFungi. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW. DR GO; GO:0006379; P:mRNA cleavage; IEA:EnsemblFungi. DR GO; GO:0006378; P:mRNA polyadenylation; IEA:EnsemblFungi. DR InterPro; IPR000571; Znf_CCCH. DR SMART; SM00356; ZnF_C3H1; 5. DR SUPFAM; SSF90229; SSF90229; 2. DR PROSITE; PS50103; ZF_C3H1; 5. PE 3: Inferred from homology; KW Complete proteome; Metal-binding; mRNA processing; Nucleus; KW Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger. FT CHAIN 1 223 mRNA 3'-end-processing protein YTH1. FT /FTId=PRO_0000238537. FT ZN_FING 32 63 C3H1-type 1. {ECO:0000255|PROSITE- FT ProRule:PRU00723}. FT ZN_FING 65 92 C3H1-type 2. {ECO:0000255|PROSITE- FT ProRule:PRU00723}. FT ZN_FING 93 121 C3H1-type 3. {ECO:0000255|PROSITE- FT ProRule:PRU00723}. FT ZN_FING 122 149 C3H1-type 4. {ECO:0000255|PROSITE- FT ProRule:PRU00723}. FT ZN_FING 151 173 C3H1-type 5. {ECO:0000255|PROSITE- FT ProRule:PRU00723}. SQ SEQUENCE 223 AA; 25709 MW; 0B668AC5D4EC15C6 CRC64; MLQLNQVIHP DTRNKRFKFE PFLLKEYNFG LDPDRPVCQF YNPSNPNNSC PNGSLCPHKH VSSMYSNKIV CKHWLRGLCK KNDHCEFLHE YNLRKMPECL FYSKNGFCTQ TPECLYLHVD PQSKIPPCSS YEKGFCPDGP KCANRHIRKI MCPLWLTGFC PKGAECDYTH PRFEAIIDRL RIKPDEDAVE EKEKVANGSD KEDQNMADAT SNGNTEEKDE SGP //