ID Q6BDC3_DANRE Unreviewed; 332 AA. AC Q6BDC3; DT 13-SEP-2004, integrated into UniProtKB/TrEMBL. DT 13-SEP-2004, sequence version 1. DT 21-MAR-2012, entry version 75. DE SubName: Full=LIM homeobox 8; DE SubName: Full=Lhx7; GN Name=lhx8a; Synonyms=lhx7, lhx8; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Whole larvae; RX PubMed=15355794; DOI=10.1016/j.ydbio.2004.07.003; RA Jackman W.R., Draper B.W., Stock D.W.; RT "Fgf signaling is required for zebrafish tooth development."; RL Dev. Biol. 274:139-157(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Testis; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Contains 1 homeobox DNA-binding domain. CC -!- SIMILARITY: Contains 2 LIM zinc-binding domains. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC117601; AAI17602.1; -; mRNA. DR EMBL; AY664404; AAT90496.1; -; mRNA. DR IPI; IPI00487481; -. DR RefSeq; NP_001003980.1; NM_001003980.1. DR UniGene; Dr.82056; -. DR ProteinModelPortal; Q6BDC3; -. DR STRING; Q6BDC3; -. DR PRIDE; Q6BDC3; -. DR GeneID; 378959; -. DR KEGG; dre:378959; -. DR CTD; 378959; -. DR ZFIN; ZDB-GENE-031008-2; lhx8a. DR HOVERGEN; HBG006261; -. DR InParanoid; Q6BDC3; -. DR KO; K09375; -. DR ArrayExpress; Q6BDC3; -. DR Bgee; Q6BDC3; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeodomain. DR InterPro; IPR009057; Homeodomain-like. DR InterPro; IPR001781; Znf_LIM. DR Gene3D; G3DSA:1.10.10.60; Homeodomain-rel; 1. DR Gene3D; G3DSA:2.10.110.10; Znf_LIM; 2. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF00412; LIM; 2. DR SMART; SM00389; HOX; 1. DR SMART; SM00132; LIM; 2. DR SUPFAM; SSF46689; Homeodomain_like; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. DR PROSITE; PS00478; LIM_DOMAIN_1; 2. DR PROSITE; PS50023; LIM_DOMAIN_2; 2. PE 2: Evidence at transcript level; KW DNA-binding; Homeobox; LIM domain; Metal-binding; Nucleus; Repeat; KW Zinc. SQ SEQUENCE 332 AA; 37388 MW; 9EEAA58759E7C962 CRC64; MYWKNEQTTS KESPSKNTAK TQDLFEEVSC SSSLSLSPSS SPHTMTEKAI CTSCGTEIVD KYLLKVNDMC WHVRCLSCSV CQTSLGRHIS CYIKEKEIFC KLDYFRKYGT RCAHCGRNIH SNDWVRRAKG NTYHLACFAC FSCKRQLSTG EEFALVDERV LCRVHYDCML DNLKRAMENG KGVNVEGAVP SEQEVNQPKP AKRARTSFTA DQLQVMQAQF AQDNNPDAQT LQKLAERTGL SRRVIQVWFQ NCRARHKKHV SPNHSSAAPV SSLQSAHLSP PLIDELQYTA FAPVDTPMLT ALHSYMDVHS PTSLVLQPLL PHSMTQLPIS HA //