ID Q6BDC3_BRARE PRELIMINARY; PRT; 332 AA. AC Q6BDC3; DT 13-SEP-2004, integrated into UniProtKB/TrEMBL. DT 13-SEP-2004, sequence version 1. DT 25-JUL-2006, entry version 22. DE Lhx7 (LIM homeobox 8). GN Name=lhx8; Synonyms=lhx7; OS Brachydanio rerio (Zebrafish) (Danio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Whole larvae; RX PubMed=15355794; DOI=10.1016/j.ydbio.2004.07.003; RA Jackman W.R., Draper B.W., Stock D.W.; RT "Fgf signaling is required for zebrafish tooth development."; RL Dev. Biol. 274:139-157(2004). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis; RG NIH MGC Project; RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY664404; AAT90496.1; -; mRNA. DR EMBL; BC117601; AAI17602.1; -; mRNA. DR UniGene; Dr.25698; -. DR Ensembl; ENSDARG00000002330; Danio rerio. DR ZFIN; ZDB-GENE-031008-2; lhx8. DR GO; GO:0005634; C:nucleus; IEA. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA. DR GO; GO:0003700; F:transcription factor activity; IEA. DR GO; GO:0008270; F:zinc ion binding; IEA. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA. DR InterPro; IPR002016; Haem_peroxidase_pln/fun/bac. DR InterPro; IPR001356; Homeobox. DR InterPro; IPR012287; Homeodomain-rel. DR InterPro; IPR009057; Homeodomain_like. DR InterPro; IPR002197; HTH_Fis. DR InterPro; IPR007107; LIM_homeo. DR InterPro; IPR001781; LIM_Zn_bd. DR Pfam; PF00046; Homeobox; 1. DR Pfam; PF00412; LIM; 2. DR PRINTS; PR00024; HOMEOBOX. DR PRINTS; PR01590; HTHFIS. DR ProDom; PD000010; Homeobox; 1. DR ProDom; PD000094; LIM; 2. DR SMART; SM00389; HOX; 1. DR SMART; SM00132; LIM; 2. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. DR PROSITE; PS00478; LIM_DOMAIN_1; 2. DR PROSITE; PS50023; LIM_DOMAIN_2; 2. DR PROSITE; PS00435; PEROXIDASE_1; UNKNOWN_1. KW Nuclear protein. SQ SEQUENCE 332 AA; 37388 MW; 9EEAA58759E7C962 CRC64; MYWKNEQTTS KESPSKNTAK TQDLFEEVSC SSSLSLSPSS SPHTMTEKAI CTSCGTEIVD KYLLKVNDMC WHVRCLSCSV CQTSLGRHIS CYIKEKEIFC KLDYFRKYGT RCAHCGRNIH SNDWVRRAKG NTYHLACFAC FSCKRQLSTG EEFALVDERV LCRVHYDCML DNLKRAMENG KGVNVEGAVP SEQEVNQPKP AKRARTSFTA DQLQVMQAQF AQDNNPDAQT LQKLAERTGL SRRVIQVWFQ NCRARHKKHV SPNHSSAAPV SSLQSAHLSP PLIDELQYTA FAPVDTPMLT ALHSYMDVHS PTSLVLQPLL PHSMTQLPIS HA //