ID Q68FI4_XENLA Unreviewed; 150 AA. AC Q68FI4; DT 11-OCT-2004, integrated into UniProtKB/TrEMBL. DT 11-OCT-2004, sequence version 1. DT 04-MAR-2015, entry version 53. DE RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301}; GN Name=arpc5 {ECO:0000313|Xenbase:XB-GENE-866317}; GN Synonyms=MGC86407 {ECO:0000313|EMBL:AAH79805.1}; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; OC Xenopus. OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH79805.1}; RN [1] {ECO:0000313|EMBL:AAH79805.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Kidney {ECO:0000313|EMBL:AAH79805.1}; RG NIH - Xenopus Gene Collection (XGC) project; RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:ABL63901.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=17178911; DOI=10.1083/jcb.200604176; RA Miyoshi T., Tsuji T., Higashida C., Hertzog M., Fujita A., RA Narumiya S., Scita G., Watanabe N.; RT "Actin turnover-dependent fast dissociation of capping protein in the RT dendritic nucleation actin network: evidence of frequent filament RT severing."; RL J. Cell Biol. 175:947-955(2006). CC -!- FUNCTION: Functions as component of the Arp2/3 complex which is CC involved in regulation of actin polymerization and together with CC an activating nucleation-promoting factor (NPF) mediates the CC formation of branched actin networks. CC {ECO:0000256|RuleBase:RU004301}. CC -!- SIMILARITY: Belongs to the ARPC5 family. CC {ECO:0000256|RuleBase:RU004301}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC079805; AAH79805.1; -; mRNA. DR EMBL; EF011868; ABL63901.1; -; mRNA. DR RefSeq; NP_001087450.1; NM_001093981.1. DR UniGene; Xl.45915; -. DR GeneID; 447274; -. DR KEGG; xla:447274; -. DR CTD; 10092; -. DR Xenbase; XB-GENE-866317; arpc5. DR HOVERGEN; HBG050583; -. DR KO; K05754; -. DR GO; GO:0005885; C:Arp2/3 protein complex; IEA:InterPro. DR GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro. DR Gene3D; 1.25.40.190; -; 1. DR InterPro; IPR006789; ARPC5. DR PANTHER; PTHR12644; PTHR12644; 1. DR Pfam; PF04699; P16-Arc; 1. DR SUPFAM; SSF69103; SSF69103; 1. PE 2: Evidence at transcript level; KW Cytoplasm {ECO:0000256|RuleBase:RU004301}; KW Cytoskeleton {ECO:0000256|RuleBase:RU004301}. SQ SEQUENCE 150 AA; 16400 MW; 686E7C42BBDF5726 CRC64; MAKNTVSARF RKVDVDEYDE NKFVDEEEAG EGQQGPDEGE VDSAIRGGNM MGALQAALKN PPINTKNQSA KDRAENLVLK VLISFKANEI EKAVQSLDKN STDLLMKYIY KGFESPSDNS SAVLLQWHEK ALAVAGVGSI VRVLTARKTV //