ID Q68FI4_XENLA Unreviewed; 150 AA. AC Q68FI4; DT 11-OCT-2004, integrated into UniProtKB/TrEMBL. DT 11-OCT-2004, sequence version 1. DT 22-JUL-2008, entry version 22. DE RecName: Full=MGC86407 protein (Actin-related protein 2/3 complex subunit 5); GN Name=MGC86407; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; OC Xenopodinae; Xenopus; Xenopus. OX NCBI_TaxID=8355; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Kidney; RG NIH - Xenopus Gene Collection (XGC) project; RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RX PubMed=17178911; DOI=10.1083/jcb.200604176; RA Miyoshi T., Tsuji T., Higashida C., Hertzog M., Fujita A., RA Narumiya S., Scita G., Watanabe N.; RT "Actin turnover-dependent fast dissociation of capping protein in the RT dendritic nucleation actin network: evidence of frequent filament RT severing."; RL J. Cell Biol. 175:947-955(2006). CC -!- FUNCTION: Functions as component of the Arp2/3 complex which is CC involved in regulation of actin polymerization and together with CC an activating nucleation-promoting factor (NPF) mediates the CC formation of branched actin networks (By similarity). CC -!- SIMILARITY: Belongs to the ARPC5 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC079805; AAH79805.1; -; mRNA. DR EMBL; EF011868; ABL63901.1; -; mRNA. DR RefSeq; NP_001087450.1; -. DR UniGene; Xl.45915; -. DR SMR; Q68FI4; 8-149. DR GeneID; 447274; -. DR KEGG; xla:447274; -. DR HOVERGEN; Q68FI4; -. DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro. DR GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro. DR InterPro; IPR006789; ARP2/3_p16_Arc. DR Gene3D; G3DSA:1.25.40.190; p16_Arc; 1. DR PANTHER; PTHR12644; p16_Arc; 1. DR Pfam; PF04699; P16-Arc; 1. PE 2: Evidence at transcript level; KW Cytoskeleton. SQ SEQUENCE 150 AA; 16400 MW; 686E7C42BBDF5726 CRC64; MAKNTVSARF RKVDVDEYDE NKFVDEEEAG EGQQGPDEGE VDSAIRGGNM MGALQAALKN PPINTKNQSA KDRAENLVLK VLISFKANEI EKAVQSLDKN STDLLMKYIY KGFESPSDNS SAVLLQWHEK ALAVAGVGSI VRVLTARKTV //