ID Q67045_9INFA PRELIMINARY; PRT; 131 AA. AC Q67045; DT 01-NOV-1996 (TrEMBLrel. 01, Created) DT 01-NOV-1996 (TrEMBLrel. 01, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE Hemagglutinin (Fragment). OS Influenza A virus (A/Adachi/2/57(H2N2)). OC Viruses; ssRNA negative-strand viruses; Orthomyxoviridae; OC Influenzavirus A; H2N2 subtype. OX NCBI_TaxID=223936; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=93233219; PubMed=7682624; RA Okuno Y., Isegawa Y., Sasao F., Ueda S.; RT "A common neutralizing epitope conserved between the hemagglutinins of RT influenza A virus H1 and H2 strains."; RL J. Virol. 67:2552-2558(1993). RN [2] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=81030852; PubMed=7421990; RA Gething M.J., Bye J., Skehel J., Waterfield M.; RT "Cloning and DNA sequence of double-stranded copies of haemagglutinin RT genes from h2 ahd h3 strains elucidates antigenic shift and drift in RT human influenza virus."; RL Nature 287:301-306(1980). CC -!- FUNCTION: Hemagglutinin is responsible for attaching the virus to CC cell receptors and for initiating infection (By similarity). CC -!- SUBUNIT: Homotrimer. Each of the monomers is formed by two chains CC (HA1 and HA2) linked by a disulfide bond (By similarity). CC -!- SIMILARITY: Belongs to the influenza viruses hemagglutinin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D13576; BAA02771.1; -. DR HSSP; P03442; 1IBN. DR GO; GO:0019031; C:viral envelope; IEA. DR GO; GO:0019058; P:viral infectious cycle; IEA. DR InterPro; IPR001364; Hemagglutn. DR InterPro; IPR000386; Hemagglutn_2. DR Pfam; PF00509; Hemagglutinin; 1. DR PRINTS; PR00329; HEMAGGLUTN12. DR PRINTS; PR00331; HEMAGGLUTN2. DR ProDom; PD000225; Hemagglutn; 1. KW Envelope protein; Hemagglutinin. FT NON_TER 1 1 FT NON_TER 131 131 SQ SEQUENCE 131 AA; 14550 MW; 243DFC623E7F2952 CRC64; NTTLPFHNVH PLTIGECPKY VKSEKLVLAT GLRNVPQIES RGLFGAIAGF IEGGWQGMVD GWYGYHHSND QGSGYAADKE STQKAFDGIT NKVNSVIEKM NTQFEAVGKE FGNLERRLEN LNKKMEDGFL D //