ID Q65ZG6_CAEEL Unreviewed; 315 AA. AC Q65ZG6; DT 11-OCT-2004, integrated into UniProtKB/TrEMBL. DT 11-OCT-2004, sequence version 1. DT 11-DEC-2019, entry version 129. DE SubName: Full=Kruppel-Like Factor (Zinc finger protein) {ECO:0000313|EMBL:CCD68190.1}; GN Name=klf-3 {ECO:0000313|EMBL:CCD68190.1, GN ECO:0000313|WormBase:F54H5.4b}; GN ORFNames=CELE_F54H5.4 {ECO:0000313|EMBL:CCD68190.1}, F54H5.4 GN {ECO:0000313|WormBase:F54H5.4b}; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; OC Caenorhabditis. OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD68190.1, ECO:0000313|Proteomes:UP000001940}; RN [1] {ECO:0000313|EMBL:CCD68190.1, ECO:0000313|Proteomes:UP000001940} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD68190.1, RC ECO:0000313|Proteomes:UP000001940}; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RA Sulson J.E., Waterston R.; RT "Genome sequence of the nematode C. elegans: a platform for investigating RT biology."; RL Science 282:2012-2018(1998). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BX284602; CCD68190.1; -; Genomic_DNA. DR RefSeq; NP_001022205.1; NM_001027034.3. DR SMR; Q65ZG6; -. DR IntAct; Q65ZG6; 6. DR STRING; 6239.F54H5.4b; -. DR PaxDb; Q65ZG6; -. DR EnsemblMetazoa; F54H5.4b.1; F54H5.4b.1; WBGene00003480. DR GeneID; 191713; -. DR KEGG; cel:CELE_F54H5.4; -. DR UCSC; F54H5.4b; c. elegans. DR CTD; 191713; -. DR WormBase; F54H5.4b; CE37379; WBGene00003480; klf-3. DR eggNOG; KOG1721; Eukaryota. DR eggNOG; COG5048; LUCA. DR HOGENOM; HOG000017449; -. DR InParanoid; Q65ZG6; -. DR KO; K09204; -. DR OMA; FQAPFSP; -. DR OrthoDB; 1201386at2759; -. DR PhylomeDB; Q65ZG6; -. DR Proteomes; UP000001940; Chromosome II. DR Bgee; WBGene00003480; Expressed in 4 organ(s), highest expression level in multi-cellular organism. DR ExpressionAtlas; Q65ZG6; baseline and differential. DR GO; GO:0005634; C:nucleus; IBA:GO_Central. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central. DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro. DR GO; GO:0045087; P:innate immune response; HEP:WormBase. DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central. DR InterPro; IPR036236; Znf_C2H2_sf. DR InterPro; IPR013087; Znf_C2H2_type. DR Pfam; PF00096; zf-C2H2; 2. DR SMART; SM00355; ZnF_C2H2; 3. DR SUPFAM; SSF57667; SSF57667; 2. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3. PE 4: Predicted; KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042}; KW Reference proteome {ECO:0000313|Proteomes:UP000001940}; KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042}; KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}. FT DOMAIN 230..259 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 260..289 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT DOMAIN 290..315 FT /note="C2H2-type" FT /evidence="ECO:0000259|PROSITE:PS50157" FT REGION 149..169 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 182..222 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 149..168 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 190..208 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 315 AA; 35903 MW; 3B9D0006D1A8D7D3 CRC64; MLKMEQSAPP RYEEDWADVY EFIERDSSRK NVPAIEAIER RLAFSPLITP NPGAKQFAPI HVPGREPPRM LLPPTPHFQA PFSPHPPPVQ QVPSYSPPHA PPSYETYPEV YYPPHIICNP YDVPTTSDRN PPYYTEVTTV SAVTLHSMTP PTHKIETPPS SPENSFGPLA SQLPAIKMEI PMHPLPHNGE LDSTRSSPSS TTSSERSPLQ RKSRIESNKR NPTDKKFVVH ACTYPGCFKK YSKSSHLKAH ERTHSGEKPF VCKWQNCSWK FARSDELTRH MRKHTGDKPF RCSLCDRNFA RSDHLSLHMK RHSTI //