ID   Q64J77_CORAM            Unreviewed;      1116 AA.
AC   Q64J77;
DT   25-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2004, sequence version 1.
DT   11-MAY-2016, entry version 56.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031};
DE            EC=2.7.7.6 {ECO:0000256|RuleBase:RU363031};
DE   Flags: Fragment;
GN   Name=rpoB {ECO:0000313|EMBL:AAS89205.1};
OS   Corynebacterium ammoniagenes (Brevibacterium ammoniagenes).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=1697 {ECO:0000313|EMBL:AAS89205.1};
RN   [1] {ECO:0000313|EMBL:AAS89205.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CIP 101283 {ECO:0000313|EMBL:AAS89205.1};
RX   PubMed=15364970; DOI=10.1128/JCM.42.9.3925-3931.2004;
RA   Khamis A., Raoult D., La Scola B.;
RT   "rpoB gene sequencing for identification of Corynebacterium species.";
RL   J. Clin. Microbiol. 42:3925-3931(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000256|RuleBase:RU363031}.
CC   -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
CC       + RNA(n+1). {ECO:0000256|RuleBase:RU363031}.
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1
CC       beta' and 1 omega subunit. When a sigma factor is associated with
CC       the core the holoenzyme is formed, which can initiate
CC       transcription. {ECO:0000256|RuleBase:RU363031}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000256|RuleBase:RU000434}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY492243; AAS89205.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q64J77; -.
DR   STRING; 649754.HMPREF0281_01714; -.
DR   eggNOG; ENOG4108IIJ; Bacteria.
DR   eggNOG; COG0085; LUCA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 2.30.150.10; -; 1.
DR   Gene3D; 2.40.270.10; -; 2.
DR   Gene3D; 2.40.50.150; -; 1.
DR   Gene3D; 3.90.1110.10; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR010243; DNA-dir_RNA_pol_bsu.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNA_pol_su2_6.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 3.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU363031};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363031};
KW   Transcription {ECO:0000256|RuleBase:RU363031};
KW   Transferase {ECO:0000256|RuleBase:RU363031}.
FT   DOMAIN       74    402       RNA_pol_Rpb2_1. {ECO:0000259|Pfam:
FT                                PF04563}.
FT   DOMAIN      160    357       RNA_pol_Rpb2_2. {ECO:0000259|Pfam:
FT                                PF04561}.
FT   DOMAIN      416    484       RNA_pol_Rpb2_3. {ECO:0000259|Pfam:
FT                                PF04565}.
FT   DOMAIN      494    560       RNA_pol_Rpb2_45. {ECO:0000259|Pfam:
FT                                PF10385}.
FT   DOMAIN      624   1041       RNA_pol_Rpb2_6. {ECO:0000259|Pfam:
FT                                PF00562}.
FT   DOMAIN     1043   1115       RNA_pol_Rpb2_7. {ECO:0000259|Pfam:
FT                                PF04560}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:AAS89205.1}.
FT   NON_TER    1116   1116       {ECO:0000313|EMBL:AAS89205.1}.
SQ   SEQUENCE   1116 AA;  124301 MW;  01A5E71051C249A0 CRC64;
     SRQTKSVANI PGAPKRYSFA KISEPIAVPG LLDLQLESFA WLIGTSEWRE RQQEERGEEH
     VSSGLEDILA ELSPIQDYSG NMSLSLSEPR FEPVKNTVDE CKEKDINYSA PLYVTAEFIN
     NDTQEIKSQT VFIGDFPMMT DEGTFIVNGT ERVVVSQLVR SPGVYFDQTI DKSTERPLHS
     VKVIPSRGAW LEFDVDKRDT VGVRIDRKRR QPVTVLLKAL GWTEQQIRDR FGFSELMMST
     LESDGIANTD EALLEIYRKQ RPGEQPTRDL AQSLLDNSFF RAKRYDLARV GRYKVNRKLG
     LGGDHEGLMT LTEEDIAVTL EYLVRLHTGE REMKAPNGEM IPVNTDDIDH FGNRRLRTVG
     ELIQNQVRVG LSRMERVVRE RMTTQDAESI TPTSLINVRP VSAAIREFFG TSQLSQFMDQ
     NNSLSGLTHK RRLSALGPGG LSRERAGIEV RDVHPSHYGR MCPIETPEGP NIGLIGSLAS
     YARVNAFGFI ETPYRKVENG RVTDEVRYLT ADEEDRYSIA QAEVEQDADG NIVGDRIEVR
     LKDGDIGVTD ANGVDYVDVS PRQMVSVGTA MIPFLEHDDA NRALMGANMQ KQAVPLVRGE
     APYVGTGMEL RAAYDAGDMV ISPKAGVVEN VNADLITIMD DEGVRDTYML RKFERTNQGT
     NYNQTPLVNM GDRVEAGQVL ADGPGTHNGE MSLGRNLLVA FMPWEGHNYE DAIILSQRIV
     EEDVLTSIHI EEHEIDARDT KLGAEEITRE IPNVSEDVLR DLDDRGIIRI GADVRAGDIL
     VGKVTPKGET ELTPEERLLR AIFGEKAREV RDTSMKVPHG ETGKVIGVAR FSREDDDDLA
     PGVNEMIRVY VAQKRKIQDG DKLAGRHGNK GVVGKVLPPE DMPFMADGTP VDVILNTHGV
     PRRMNIGQVL ELHLGWLAHT GWTVDTEDPK NEELLKTLPE ELYDVPADSL TATPVFDGAT
     NEEISRLLAS SKPNRDGDVM VDEDGKTVLF DGRSGEPYQY PISVGFMYIL KLHHLIDEKI
     HARSTGPYSM ITQQPLGGKA QFGGQRFGEM EVWAMQAYGA AYTLQELLTI KSDDVVGRVK
     VYEAIVKGDN IPDPGIPESF KVLLKELQSL CLNVEV
//