ID SYB2_MOUSE STANDARD; PRT; 115 AA. AC Q64357; DT 01-NOV-1997 (REL. 35, CREATED) DT 01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE) DT 15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE) DE SYNAPTOBREVIN 2 (VESICLE ASSOCIATED MEMBRANE PROTEIN 2) (VAMP-2). GN SYB2. OS MUS MUSCULUS (MOUSE), AND RATTUS NORVEGICUS (RAT). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; MAMMALIA; EUTHERIA; OC RODENTIA; SCIUROGNATHI; MURIDAE; MURINAE; MUS. RN [1] RP SEQUENCE FROM N.A. RC SPECIES=RAT; RX MEDLINE; 89291844. RA ELFERINK L.A., TRIMBLE W.S., SCHELLER R.H.; RT "Two vesicle-associated membrane protein genes are differentially RT expressed in the rat central nervous system."; RL J. BIOL. CHEM. 264:11061-11064(1989). RN [2] RP SEQUENCE FROM N.A. RC SPECIES=MOUSE; RA MARTIN S., TELLAM J.T., LIVINGTON C., SLOT J.W., GOULD G.W., RA JAMES D.E.; RL SUBMITTED (JUL-1996) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: INTRINSIC MEMBRANE PROTEIN OF SMALL SYNAPTIC CC VESICLES. CC -!- SUBCELLULAR LOCATION: TYPE II MEMBRANE PROTEIN. NEURONAL SYNAPTIC CC VESICLES. CC -!- TISSUE SPECIFICITY: NERVOUS SYSTEM SPECIFIC. A HIGHER LEVEL CC EXPRESSION IS SEEN IN THE BRAIN AS COMPARED TO THE SPINAL CORD. CC -!- SIMILARITY: BELONGS TO THE SYNAPTOBREVIN FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M24105; G207627; -. DR EMBL; U60150; G1402799; -. DR MGD; MGI:98459; SYB2. DR PROSITE; PS00417; SYNAPTOBREVIN; 1. DR PFAM; PF00957; synaptobrevin; 1. KW SYNAPSE; TRANSMEMBRANE; SYNAPTOSOME; MULTIGENE FAMILY; ACETYLATION; KW POLYMORPHISM; SIGNAL-ANCHOR. FT INIT_MET 0 0 BY SIMILARITY. FT DOMAIN 1 93 CYTOPLASMIC (PROBABLE). FT TRANSMEM 94 113 SIGNAL-ANCHOR (TYPE-II MEMBRANE PROTEIN) FT (POTENTIAL). FT DOMAIN 114 115 VESICULAR (PROBABLE). FT MOD_RES 1 1 ACETYLATION (BY SIMILARITY). FT VARIANT 110 110 I -> II. FT VARIANT 111 111 V -> I. SQ SEQUENCE 115 AA; 12559 MW; 45F5B2AF CRC32; SATAATVPPA APAGEGGPPA PPPNLTSNRR LQQTQAQVDE VVDIMRVNVD KVLERDQKLS ELDDRADALQ AGASQFETSA AKLKRKYWWK NLKMMIILGV ICAIILIIII VYFST //