ID CHCH6_DANRE Reviewed; 239 AA. AC Q63ZW2; DT 18-APR-2012, integrated into UniProtKB/Swiss-Prot. DT 25-OCT-2004, sequence version 1. DT 11-DEC-2013, entry version 51. DE RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial; GN Name=chchd6; ORFNames=zgc:91802; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., RA Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., RA Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., RA Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., RA Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., RA Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., RA Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., RA Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., RA Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., RA Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., RA Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., RA Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., RA Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., RA Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., RA Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Required for maintaining mitochondrial crista CC morphology, ATP production and oxygen consumption (By similarity). CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Lipid-anchor CC (By similarity). CC -!- SIMILARITY: Belongs to the CHCHD6 family. CC -!- SIMILARITY: Contains 1 CHCH domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL954678; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC082793; AAH82793.1; -; mRNA. DR IPI; IPI00481256; -. DR RefSeq; NP_001005584.1; NM_001005584.1. DR RefSeq; XP_005162369.1; XM_005162312.1. DR UniGene; Dr.76072; -. DR DNASU; 449542; -. DR Ensembl; ENSDART00000143933; ENSDARP00000116560; ENSDARG00000003206. DR GeneID; 449542; -. DR KEGG; dre:449542; -. DR CTD; 449542; -. DR ZFIN; ZDB-GENE-040930-2; chchd6a. DR eggNOG; NOG325011; -. DR GeneTree; ENSGT00390000000903; -. DR HOGENOM; HOG000252969; -. DR HOVERGEN; HBG050936; -. DR InParanoid; Q63ZW2; -. DR KO; K17564; -. DR OMA; SKMESTI; -. DR OrthoDB; EOG7NW6C3; -. DR NextBio; 20832661; -. DR ArrayExpress; Q63ZW2; -. DR Bgee; Q63ZW2; -. DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB. DR GO; GO:0042407; P:cristae formation; ISS:UniProtKB. DR GO; GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB. DR InterPro; IPR007964; DUF737. DR Pfam; PF05300; DUF737; 1. PE 2: Evidence at transcript level; KW Coiled coil; Complete proteome; Disulfide bond; Lipoprotein; Membrane; KW Mitochondrion; Mitochondrion inner membrane; Myristate; KW Reference proteome. FT INIT_MET 1 1 Removed (Potential). FT CHAIN 2 239 Coiled-coil-helix-coiled-coil-helix FT domain-containing protein 6, FT mitochondrial. FT /FTId=PRO_0000416910. FT DOMAIN 188 229 CHCH. FT COILED 79 166 Potential. FT LIPID 2 2 N-myristoyl glycine (Potential). FT DISULFID 195 226 By similarity. FT DISULFID 205 216 By similarity. SQ SEQUENCE 239 AA; 27540 MW; A215A00FAD26DBEA CRC64; MGSGESTTRR VSFGLDEDDR VRILRGVKLS EDVLQRMRNT NADPRPPANN KENQGHQTRT PSTSDAQAPK TQAKTTFPDS KEELKKRYEQ QQAIIQEELA RIARKEREAA RQDISRAVQR ERAQTRQESE RAKQLGKQLD KKEAELKALE AFYQEQITQL EKKNEERFRM SAEQFHAAAT RSEANIKARN VEPVCLNLQA QILNCYRENR EQTLQCSDLA KEYMQCINAA KKNLLVNHG //