ID C3L1_MOUSE STANDARD; PRT; 381 AA. AC Q61362; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Chitinase-3 like protein 1 precursor (Cartilage glycoprotein-39) DE (GP-39) (BRP39 protein). GN CHI3L1 OR BRP39. OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=FVB/N; TISSUE=Breast; RX MEDLINE=95060797; PubMed=7970700; RA Morrison B.W., Leder P.; RT "neu and ras initiate murine mammary tumors that share genetic markers RT generally absent in c-myc and int-2-initiated tumors."; RL Oncogene 9:3417-3426(1994). CC -!- FUNCTION: May play an important role in the capacity of cells to CC respond to and cope with changes in their environment (By CC similarity). CC -!- SUBCELLULAR LOCATION: Extracellular (By similarity). CC -!- SIMILARITY: Belongs to family 18 of glycosyl hydrolases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X93035; CAA63603.1; -. DR PIR; S61551; S61551. DR MGD; MGI:1340899; Chi3l1. DR InterPro; IPR001223; Glyco_hydro_18. DR InterPro; IPR001579; Glyco_hydro_18AS. DR Pfam; PF00704; Glyco_hydro_18; 1. DR ProDom; PD000471; Glyco_hydro_18; 1. DR SMART; SM00636; Glyco_18; 1. DR PROSITE; PS01095; CHITINASE_18; FALSE_NEG. KW Glycoprotein; Signal. FT SIGNAL 1 21 Potential. FT CHAIN 22 381 CHITINASE-3 LIKE PROTEIN 1. FT CARBOHYD 60 60 N-LINKED (GLCNAC...) (POTENTIAL). SQ SEQUENCE 381 AA; 43001 MW; EF6581E8184F0450 CRC64; MGMRAALTGF AVLMLLQSCS AYKLVCYFTS WSQYREGVGS FLPDAIQPFL CTHIIYSFAN ISSDNMLSTW EWNDESNYDK LNKLKTRNTN LKTLLSVGGW KFGEKRFSEI ASNTERRTAF VRSVAPFLRS YGFDGLDLAW LYPRLRDKQY FSTLIKELNA EFTKEVQPGR EKLLLSAALS AGKVAIDTGY DIAQIAQHLD FINLMTYDFH GVWRQITGHH SPLFQGQKDT RFDRYSNVNY AVQYMIRLGA QASKLLMGIP TFGKSFTLAS SENQLGAPIS GEGLPGRFTK EAGTLAYYEI CDFLKGAEVH RLSNEKVPFA TKGNQWVGYE HKESVKNKVG FLKEKKLAGA MVWALDLDDF QGTCQPKEFF PLTNAIKDAL A //