ID LC4S_MOUSE STANDARD; PRT; 150 AA. AC Q60860; DT 01-NOV-1997 (REL. 35, CREATED) DT 01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE LEUKOTRIENE C4 SYNTHASE (EC 2.5.1.37) (LEUKOTRIENE-C(4) SYNTHASE) DE (LTC4 SYNTHASE). GN LTC4S. OS MUS MUSCULUS (MOUSE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; RODENTIA. RN [1] RP SEQUENCE FROM N.A. RA LAM B.K.; RL SUBMITTED (SEP-1995) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- CATALYTIC ACTIVITY: LEUKOTRIENE A4 + GLUTATHIONE = LEUKOTRIENE C4 CC + H(2)O. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL). CC -!- SIMILARITY: BELONGS TO THE FLAP/LTC4S FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U27195; G973222; -. DR MGD; MGI:107498; LTC4S. DR PROSITE; PS01297; FLAP_GST2_LTC4S; 1. KW TRANSFERASE; TRANSMEMBRANE; LEUKOTRIENE BIOSYNTHESIS. FT TRANSMEM 7 27 POTENTIAL. FT TRANSMEM 68 88 POTENTIAL. FT TRANSMEM 115 135 POTENTIAL. SQ SEQUENCE 150 AA; 16814 MW; 87517D00 CRC32; MKDEVALLAT VTLVGVLLQA YFSLQVISAR RAFHVSPPLT SGPPEFERVF RAQVNCSEYF PLFLATLWVA GIFFHEGAAA LCGLFYLFAR LRYFQGYARS AQLRLTPLYA SARALWLLVA MAALGLLVHF LPGTLRTALF RWLQMLLPMA //