ID   Q5WDG8_BACSK            Unreviewed;       957 AA.
AC   Q5WDG8;
DT   23-NOV-2004, integrated into UniProtKB/TrEMBL.
DT   23-NOV-2004, sequence version 1.
DT   22-FEB-2012, entry version 59.
DE   SubName: Full=Excinuclease ABC subunit A UvrA;
GN   Name=uvrA; OrderedLocusNames=ABC3058;
OS   Bacillus clausii (strain KSM-K16).
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii
RT   KSM-K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrA is an ATPase and a DNA-binding
CC       protein. A damage recognition complex composed of 2 UvrA and 2
CC       UvrB subunits scans DNA for abnormalities. When the presence of a
CC       lesion has been verified by UvrB, the UvrA molecules dissociate
CC       (By similarity).
CC   -!- SUBUNIT: Forms a heterotetramer with UvrB during the search for
CC       lesions (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
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DR   EMBL; AP006627; BAD65592.1; -; Genomic_DNA.
DR   RefSeq; YP_176553.1; NC_006582.1.
DR   ProteinModelPortal; Q5WDG8; -.
DR   SMR; Q5WDG8; 4-949.
DR   STRING; Q5WDG8; -.
DR   EnsemblBacteria; EBBACT00000047098; EBBACP00000045859; EBBACG00000047089.
DR   GeneID; 3203580; -.
DR   GenomeReviews; AP006627_GR; ABC3058.
DR   KEGG; bcl:ABC3058; -.
DR   PATRIC; 18925830; VBIBacCla58185_3264.
DR   eggNOG; COG0178; -.
DR   HOGENOM; HBG284763; -.
DR   KO; K03701; -.
DR   OMA; GAIKGWD; -.
DR   ProtClustDB; PRK00349; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   HAMAP; MF_00205; UvrA; 1; -.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   InterPro; IPR004602; UvrA_ABC.
DR   Gene3D; G3DSA:3.30.1490.20; ATP_grasp_subdomain_1; 2.
DR   Pfam; PF00005; ABC_tran; 2.
DR   SMART; SM00382; AAA; 2.
DR   TIGRFAMs; TIGR00630; Uvra; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; DNA damage; DNA excision;
KW   DNA repair; DNA-binding; Excision nuclease; Metal-binding;
KW   Nucleotide-binding; Repeat; SOS response; Zinc; Zinc-finger.
SQ   SEQUENCE   957 AA;  106013 MW;  5502EDC703CF6891 CRC64;
     MAHEQIVVKG ARSNNLKNMD VTIPRDKLVV LTGLSGSGKS SLAFDTIYAE GQRRYVESLS
     AYARQFLGQM DKPDVDSIEG LSPAISIDQK TTSRNPRSTV GTVTEIHDYL RLLYARIGRP
     VCPRHGIEIS SQTIEQMVDR LLEYPERTKM QILAPLVSGR KGTHVKTLEQ IKRDGYVRIR
     VDGEMREASE EIELDKNKKH TIEVVIDRIV IKEGVQARIA DSLETALTLA GGRVLVDVIG
     EEELLFSQQH ACPECGFSIP ELEPRLFSFN SPFGACPSCD GLGSKQEVDS ELVVPDPSRS
     LREHALAPWE PTSSNYYPQL LQAVCDHFGI DMDVPFEKLP ATQQQILLEG SGKEKIFFRY
     ENDFGRVHEH TIVFEGVLAN VARRYRETSS DYIREQMEMY MSQKKCPTCK GYRLKKEALA
     VFVGGKHLGE VSQMTCTDAI QFVKSLDLTE KERAIARLII KEIEDRLGFL VNVGLDYLTL
     SRAAGTLSGG EAQRIRLATQ IGSSLMGVLY ILDEPSIGLH QRDNDRLIET LKHMRDLGNT
     LIVVEHDEDT MLAADHIIDI GPGAGMHGGY ITAQGTPKEL TENPHSLTGK YLSGEKFIPV
     PRERRPLTDR SFTVKKASAN NLKNIDVTFP LGVFIAVTGV SGSGKSTLVN EIVHKALAQR
     IHRAKAKPGP HKEIIGIDEM DKVIDIDQSP IGRTPRSNPA TYTSMFDDIR DVFAMTNEAK
     VRGYKKGRFS FNVKGGRCEA CKGDGIIKIE MHFLPDVYVP CEVCHGKRYN RETLEVTYKG
     KTIADVLEMT IEEGAEFFAS IPKINRKIQT LIDVGLGYLK MGQPATTLSG GEAQRVKLAS
     QLHKRSTGRT LYILDEPTTG LHVDDIARLL KVLQRLVDNG DTVLVIEHNL DVIKTADHII
     DLGPEGGKNG GTIVAEGTPE HVAETSASYT GAYLKPILAR DKARQEALFA GAEQKSS
//