ID Q5VT16_HUMAN PRELIMINARY; PRT; 926 AA. AC Q5VT16; DT 01-FEB-2005 (TrEMBLrel. 29, Created) DT 01-FEB-2005 (TrEMBLrel. 29, Last sequence update) DT 07-FEB-2006 (TrEMBLrel. 32, Last annotation update) DE Calcium/calmodulin-dependent serine protein kinase (MAGUK DE family). GN Name=CASK; ORFNames=RP11-540L11.1-007; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RA Heath P.; RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RA Corby N.; RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Bird C.; RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE. RA Whitehead S.; RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL603754; CAH71240.1; JOINED; Genomic_DNA. DR EMBL; AL627402; CAH71240.1; -; Genomic_DNA. DR EMBL; AL158144; CAI42763.1; -; Genomic_DNA. DR EMBL; AL445239; CAI42763.1; JOINED; Genomic_DNA. DR EMBL; AL627402; CAI42763.1; JOINED; Genomic_DNA. DR EMBL; AL353691; CAI42245.1; -; Genomic_DNA. DR EMBL; AL445239; CAI42245.1; JOINED; Genomic_DNA. DR EMBL; AL158144; CAI41093.1; JOINED; Genomic_DNA. DR EMBL; AL445239; CAI41093.1; -; Genomic_DNA. DR EMBL; AL158144; CAH71240.1; JOINED; Genomic_DNA. DR EMBL; AL603754; CAI41635.1; -; Genomic_DNA. DR EMBL; AL627402; CAI41635.1; JOINED; Genomic_DNA. DR EMBL; AL445239; CAI41635.1; JOINED; Genomic_DNA. DR EMBL; AL353691; CAI41635.1; JOINED; Genomic_DNA. DR EMBL; AL158144; CAI41635.1; JOINED; Genomic_DNA. DR EMBL; AL603754; CAI41093.1; JOINED; Genomic_DNA. DR EMBL; AL627402; CAI41093.1; JOINED; Genomic_DNA. DR EMBL; AL353691; CAI41093.1; JOINED; Genomic_DNA. DR EMBL; AL445239; CAH71240.1; JOINED; Genomic_DNA. DR EMBL; AL353691; CAH71240.1; JOINED; Genomic_DNA. DR EMBL; AL627402; CAI42245.1; JOINED; Genomic_DNA. DR EMBL; AL603754; CAI42245.1; JOINED; Genomic_DNA. DR EMBL; AL158144; CAI42245.1; JOINED; Genomic_DNA. DR EMBL; AL603754; CAI42763.1; JOINED; Genomic_DNA. DR EMBL; AL353691; CAI42763.1; JOINED; Genomic_DNA. DR SMR; Q5VT16; 339-394, 405-454, 487-572, 739-914. DR Ensembl; ENSG00000147044; Homo sapiens. DR GO; GO:0005524; F:ATP binding; IEA. DR GO; GO:0005515; F:protein binding; IEA. DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA. DR GO; GO:0004713; F:protein-tyrosine kinase activity; IEA. DR GO; GO:0006468; P:protein amino acid phosphorylation; IEA. DR InterPro; IPR008144; Guanylate_kin. DR InterPro; IPR008145; Guanylt/Ca. DR InterPro; IPR004172; L27. DR InterPro; IPR001478; PDZ. DR InterPro; IPR000719; Prot_kinase. DR InterPro; IPR002290; Ser_thr_pkinase. DR InterPro; IPR001452; SH3. DR InterPro; IPR011511; SH3_2. DR InterPro; IPR001245; Tyr_pkinase. DR Pfam; PF00625; Guanylate_kin; 1. DR Pfam; PF02828; L27; 2. DR Pfam; PF00595; PDZ; 1. DR Pfam; PF00069; Pkinase; 1. DR Pfam; PF07653; SH3_2; 1. DR PRINTS; PR00452; SH3DOMAIN. DR ProDom; PD000001; Prot_kinase; 1. DR ProDom; PD000066; SH3; 1. DR SMART; SM00072; GuKc; 1. DR SMART; SM00569; L27; 2. DR SMART; SM00228; PDZ; 1. DR SMART; SM00220; S_TKc; 1. DR SMART; SM00326; SH3; 1. DR SMART; SM00219; TyrKc; 1. DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1. DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1. DR PROSITE; PS51022; L27; 2. DR PROSITE; PS50106; PDZ; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS50002; SH3; 1. KW Kinase. SQ SEQUENCE 926 AA; 105123 MW; 6C02008CE52728BA CRC64; MADDDVLFED VYELCEVIGK GPFSVVRRCI NRETGQQFAV KIVDVAKFTS SPGLSTEDLK REASICHMLK HPHIVELLET YSSDGMLYMV FEFMDGADLC FEIVKRADAG FVYSEAVASH YMRQILEALR YCHDNNIIHR DVKPHCVLLA SKENSAPVKL GGFGVAIQLG ESGLVAGGRV GTPHFMAPEV VKREPYGKPV DVWGCGVILF ILLSGCLPFY GTKERLFEGI IKGKYKMNPR QWSHISESAK DLVRRMLMLD PAERITVYEA LNHPWLKERD RYAYKIHLPE TVEQLRKFNA RRKLKGAVLA AVSSHKFNSF YGDPPEELPD FSEDPTSSGL LAAERAVSQV LDSLEEIHAL TDCSEKDLDF LHSVFQDQHL HTLLDLYDKI NTKSSPQIRN PPSDAVQRAK EVLEEISCYP ENNDAKELKR ILTQPHFMAL LQTHDVVAHE VYSDEALRVT PPPTSPYLNG DSPESANGDM DMENVTRVRL VQFQKNTDEP MGITLKMNEL NHCIVARIMH GGMIHRQGTL HVGDEIREIN GISVANQTVE QLQKMLREMR GSITFKIVPS YRTQSSSCER DSPSTSRQSP ANGHSSTNNS VSDLPSTTQP KGRQIYVRAQ FEYDPAKDDL IPCKEAGIRF RVGDIIQIIS KDDHNWWQGK LENSKNGTAG LIPSPELQEW RVACIAMEKT KQEQQASCTW FGKKKKQYKD KYLAKHNAVF DQLDLVTYEE VVKLPAFKRK TLVLLGAHGV GRRHIKNTLI TKHPDRFAYP IPHTTRPPKK DEENGKNYYF VSHDQMMQDI SNNEYLEYGS HEDAMYGTKL ETIRKIHEQG LIAILDVEPQ ALKVLRTAEF APFVVFIAAP TITPGLNEDE SLQRLQKESD ILQRTYAHYF DLTIINNEID ETIRHLEEAV ELVCTAPQWV PVSWVY //