ID MF2AA_DANRE Reviewed; 532 AA. AC Q5U3U7; DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot. DT 07-DEC-2004, sequence version 1. DT 06-FEB-2013, entry version 51. DE RecName: Full=Major facilitator superfamily domain-containing protein 2A-A; GN Name=mfsd2aa; Synonyms=mfsd2a; ORFNames=zgc:101615; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Embryo; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein CC (Potential). CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC085388; AAH85388.1; -; mRNA. DR IPI; IPI00510918; -. DR RefSeq; NP_001007452.1; NM_001007451.1. DR UniGene; Dr.86869; -. DR ProteinModelPortal; Q5U3U7; -. DR GeneID; 492810; -. DR KEGG; dre:492810; -. DR CTD; 492810; -. DR ZFIN; ZDB-GENE-041114-166; mfsd2aa. DR eggNOG; COG2211; -. DR HOGENOM; HOG000294186; -. DR HOVERGEN; HBG080097; -. DR InParanoid; Q5U3U7; -. DR OrthoDB; EOG4X97HB; -. DR NextBio; 20865308; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR016196; MFS_dom_general_subst_transpt. DR SUPFAM; SSF103473; MFS_gen_substrate_transporter; 1. DR PROSITE; PS50850; MFS; FALSE_NEG. PE 2: Evidence at transcript level; KW Complete proteome; Membrane; Reference proteome; Transmembrane; KW Transmembrane helix; Transport. FT CHAIN 1 532 Major facilitator superfamily domain- FT containing protein 2A-A. FT /FTId=PRO_0000273390. FT TRANSMEM 47 67 Helical; (Potential). FT TRANSMEM 69 89 Helical; (Potential). FT TRANSMEM 119 139 Helical; (Potential). FT TRANSMEM 144 164 Helical; (Potential). FT TRANSMEM 248 268 Helical; (Potential). FT TRANSMEM 303 323 Helical; (Potential). FT TRANSMEM 336 356 Helical; (Potential). FT TRANSMEM 362 382 Helical; (Potential). FT TRANSMEM 385 405 Helical; (Potential). FT TRANSMEM 429 449 Helical; (Potential). FT TRANSMEM 476 496 Helical; (Potential). SQ SEQUENCE 532 AA; 59266 MW; 387709380163A7F2 CRC64; MARGEGAEQF SSGLLPTAKS VTQNEIKMVK LPKQQERKRA LTVWSKVCFA IGGAPYQITG TALGFFLQIF LLDVAQLNPL NASVILFVGR AWDAVTDPTV GFLVSRTPWT RHGRMMPWIL VSTIPAVLCY FLIWVVPPIE QGKMMWYLLF YCLFQTLQTC FHVPYSALTM FISTEQRERD SATAYRMTVE VFGTVVGTAI QGQIVGMANT PCKNNTSPNN SSNDLIQSNN SHIPLKSNIF DERCAYMIAS AVISLIYVVC AAVLFFGVRE QDVQGELKAQ KRVSFQKGLR LVMGHGPYVK LVLAFLFTSL AFMLLEGNFA VFIKYTLGFR EDFQNILLVI MVSATVSIPM WQWFLCRFGK KTAVYIGITW AVPFMILVVS VNSSLIVSYI VSIAAGVSVG AAFLLPWSML PDVVDDFKLQ NPTSQGHEAI FYSFYVFFTK FASGVSLGVS TLALSFAGYE TGVCVQSDSV NLTLKLLVSA APVSLIALGL LIFMTYPIDE ERREYNNKQL QLLLRNEEEE DEMEVLKPDI TA //