ID Q5T5P1_HUMAN Unreviewed; 933 AA. AC Q5T5P1; DT 21-DEC-2004, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 2. DT 31-JUL-2019, entry version 97. DE SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000365639}; DE Flags: Fragment; GN Name=KIAA1217 {ECO:0000313|Ensembl:ENSP00000365639}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000365639, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000365639, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15164054; DOI=10.1038/nature02462; RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P., RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., RA Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., RA Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., RA Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., RA Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., RA Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., RA Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., RA Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., RA Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., RA Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., RA Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., RA Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., RA Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., RA Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., RA Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., RA Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., RA Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., RA Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., RA Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., RA Doucette-Stamm L., Beck S., Smith D.R., Rogers J.; RT "The DNA sequence and comparative analysis of human chromosome 10."; RL Nature 429:375-381(2004). RN [2] {ECO:0000213|PubMed:15951569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=15951569; DOI=10.1074/mcp.M500089-MCP200; RA Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J., RA Lauffenburger D.A., White F.M.; RT "Time-resolved mass spectrometry of tyrosine phosphorylation sites in RT the epidermal growth factor receptor signaling network reveals dynamic RT modules."; RL Mol. Cell. Proteomics 4:1240-1250(2005). RN [3] {ECO:0000313|Ensembl:ENSP00000365639} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [4] {ECO:0000213|PubMed:23186163} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=23186163; RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., RA Mohammed S.; RT "Toward a comprehensive characterization of a human cancer cell RT phosphoproteome."; RL J. Proteome Res. 12:260-271(2013). RN [5] {ECO:0000213|PubMed:24275569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014; RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., RA Wang L., Ye M., Zou H.; RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human RT liver phosphoproteome."; RL J. Proteomics 96:253-262(2014). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC063961; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL157781; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL353583; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL353650; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL355977; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL356113; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL356477; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL391499; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL392104; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR jPOST; Q5T5P1; -. DR MaxQB; Q5T5P1; -. DR PeptideAtlas; Q5T5P1; -. DR PRIDE; Q5T5P1; -. DR ProteomicsDB; 64536; -. DR Ensembl; ENST00000376456; ENSP00000365639; ENSG00000120549. DR UCSC; uc057sgy.1; human. DR HGNC; HGNC:25428; KIAA1217. DR OpenTargets; ENSG00000120549; -. DR eggNOG; ENOG410IG2A; Eukaryota. DR eggNOG; ENOG410ZC52; LUCA. DR GeneTree; ENSGT00940000156098; -. DR HOGENOM; HOG000293351; -. DR ChiTaRS; KIAA1217; human. DR Proteomes; UP000005640; Chromosome 10. DR Bgee; ENSG00000120549; Expressed in 195 organ(s), highest expression level in oviduct epithelium. DR ExpressionAtlas; Q5T5P1; baseline and differential. DR GO; GO:0048706; P:embryonic skeletal system development; IEA:InterPro. DR InterPro; IPR022782; AIP3-like_C. DR InterPro; IPR026725; Skt. DR PANTHER; PTHR22741:SF11; PTHR22741:SF11; 2. DR Pfam; PF03915; AIP3; 2. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|EPD:Q5T5P1, KW ECO:0000213|MaxQB:Q5T5P1, ECO:0000213|PeptideAtlas:Q5T5P1, KW ECO:0000213|ProteomicsDB:Q5T5P1}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 188 264 AIP3. {ECO:0000259|Pfam:PF03915}. FT DOMAIN 573 743 AIP3. {ECO:0000259|Pfam:PF03915}. FT REGION 1 79 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 112 177 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 290 331 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 456 476 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 491 510 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT REGION 813 838 Disordered. {ECO:0000256|SAM:MobiDB- FT lite}. FT COILED 611 648 {ECO:0000256|SAM:Coils}. FT COMPBIAS 34 48 Polyampholyte. {ECO:0000256|SAM:MobiDB- FT lite}. FT COMPBIAS 49 64 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 162 177 Polar. {ECO:0000256|SAM:MobiDB-lite}. FT COMPBIAS 300 327 Pro-rich. {ECO:0000256|SAM:MobiDB-lite}. FT NON_TER 933 933 {ECO:0000313|Ensembl:ENSP00000365639}. SQ SEQUENCE 933 AA; 103666 MW; 5D1C4D1B91D13D56 CRC64; MEENESQKCE PCLPYSADRR QMQEQGKGNL HVTSPEDAEC RRTKERLSNG NSRGSVSKSS RNIPRRHTLG GPRSSKEILG MQTSEMDRKR EAFLEHLKQK YPHHASAIMG HQERLRDQTR SPKLSHSPQP PSLGDPVEHL SETSADSLEA MSEGDAPTPF SRGSRTRASL PVVRSTNQTK ERSLGVLYLQ YGDETKQLRM PNEITSADTI RALFVSAFPQ QLTMKMLESP SVAIYIKDES RNVYYELNDV RNIQDRSLLK VYNKDPAHAF NHTPKTMNGD MRMQRELVYA RGDGPGAPRP GSTAHPPHAI PNSPPSTPVP HSMPPSPSRI PYGGTRSMVV PGNATIPRDR ISSLPVSRPI SPSPSAILER RDVKPDEDMS GKNIAMYRNE GFYADPYLYH EGRMSIASSH GGHPLDVPDH IIAYHRTAIR SASAYCNPSM QAEMHMEQSL YRQKSRKYPD SHLPTLGSKT PPASPHRVSD LRMIDMHAHY NAHGPPHTMQ PDRASPSRQA FKKEPGTLVY IEKPRSAAGL SSLVDLGPPL MEKQVFAYST ATIPKDRETS EKMMKTTANR NHTDSAGTPH VSGGKMLSAL ESTVPPSQPP PVGTSAIHMS LLEMRRSVAE LRLQLQQMRQ LQLQNQELLR AMMKKAELEI SGKVMETMKR LEDPVQRQRV LVEQERQKYL HEEEKIVKKL CELEDFVEDL KKDSTAASRL VTLKDVEDGA FLLRQVGEAV ATLKGEFPTL QNKMRAILRI EVEAVRFLKE EPHKLDSLLK RVRSMTDVLT MLRRHVTDGL LKGTDAAQAA QYMAMEKATA AEVLKSQEEA AHTSGQPFHS TGAPGDAKSE VVPLSGMMVR HAQSSPVVIQ PSQHSVALLN PAQNLPHVAS SPAVPQEATS TLQMSQAPQS PQIPMNGSAM QSLFIEEIHS VSAKNRAVSI EKA //