ID Q5T5P1_HUMAN Unreviewed; 933 AA. AC Q5T5P1; DT 21-DEC-2004, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 2. DT 07-SEP-2016, entry version 81. DE SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000365639}; DE Flags: Fragment; GN Name=KIAA1217 {ECO:0000313|Ensembl:ENSP00000365639}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000365639, ECO:0000313|Proteomes:UP000005640}; RN [1] {ECO:0000313|Ensembl:ENSP00000365639, ECO:0000313|Proteomes:UP000005640} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15164054; DOI=10.1038/nature02462; RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P., RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., RA Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., RA Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., RA Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., RA Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., RA Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., RA Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., RA Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., RA Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., RA Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., RA Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., RA Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., RA Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., RA Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., RA Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., RA Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., RA Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., RA Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., RA Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., RA Doucette-Stamm L., Beck S., Smith D.R., Rogers J.; RT "The DNA sequence and comparative analysis of human chromosome 10."; RL Nature 429:375-381(2004). RN [2] {ECO:0000213|PubMed:15951569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=15951569; DOI=10.1074/mcp.M500089-MCP200; RA Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J., RA Lauffenburger D.A., White F.M.; RT "Time-resolved mass spectrometry of tyrosine phosphorylation sites in RT the epidermal growth factor receptor signaling network reveals dynamic RT modules."; RL Mol. Cell. Proteomics 4:1240-1250(2005). RN [3] {ECO:0000313|Ensembl:ENSP00000365639} RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [4] {ECO:0000213|PubMed:23186163} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=23186163; RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., RA Mohammed S.; RT "Toward a comprehensive characterization of a human cancer cell RT phosphoproteome."; RL J. Proteome Res. 12:260-271(2013). RN [5] {ECO:0000213|PubMed:24275569} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014; RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., RA Wang L., Ye M., Zou H.; RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human RT liver phosphoproteome."; RL J. Proteomics 96:253-262(2014). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. {ECO:0000313|Ensembl:ENSP00000365639}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC063961; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL157781; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL353583; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL353650; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL355977; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL356113; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL356477; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL391499; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL392104; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; Q5T5P1; -. DR STRING; 9606.ENSP00000365637; -. DR PaxDb; Q5T5P1; -. DR PeptideAtlas; Q5T5P1; -. DR PRIDE; Q5T5P1; -. DR Ensembl; ENST00000376456; ENSP00000365639; ENSG00000120549. DR UCSC; uc057sgy.1; human. DR HGNC; HGNC:25428; KIAA1217. DR eggNOG; ENOG410IG2A; Eukaryota. DR eggNOG; ENOG410ZC52; LUCA. DR GeneTree; ENSGT00390000012399; -. DR HOGENOM; HOG000293351; -. DR HOVERGEN; HBG019587; -. DR ChiTaRS; KIAA1217; human. DR Proteomes; UP000005640; Chromosome 10. DR Bgee; ENSG00000120549; -. DR ExpressionAtlas; Q5T5P1; baseline and differential. DR GO; GO:0048706; P:embryonic skeletal system development; IEA:InterPro. DR InterPro; IPR022782; AIP3_C. DR InterPro; IPR026725; Skt. DR PANTHER; PTHR22741:SF4; PTHR22741:SF4; 1. DR Pfam; PF03915; AIP3; 2. PE 1: Evidence at protein level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000005640}; KW Proteomics identification {ECO:0000213|EPD:Q5T5P1, KW ECO:0000213|MaxQB:Q5T5P1, ECO:0000213|PeptideAtlas:Q5T5P1}; KW Reference proteome {ECO:0000313|Proteomes:UP000005640}. FT DOMAIN 188 264 AIP3. {ECO:0000259|Pfam:PF03915}. FT DOMAIN 573 743 AIP3. {ECO:0000259|Pfam:PF03915}. FT COILED 611 648 {ECO:0000256|SAM:Coils}. FT NON_TER 933 933 {ECO:0000313|Ensembl:ENSP00000365639}. SQ SEQUENCE 933 AA; 103666 MW; 5D1C4D1B91D13D56 CRC64; MEENESQKCE PCLPYSADRR QMQEQGKGNL HVTSPEDAEC RRTKERLSNG NSRGSVSKSS RNIPRRHTLG GPRSSKEILG MQTSEMDRKR EAFLEHLKQK YPHHASAIMG HQERLRDQTR SPKLSHSPQP PSLGDPVEHL SETSADSLEA MSEGDAPTPF SRGSRTRASL PVVRSTNQTK ERSLGVLYLQ YGDETKQLRM PNEITSADTI RALFVSAFPQ QLTMKMLESP SVAIYIKDES RNVYYELNDV RNIQDRSLLK VYNKDPAHAF NHTPKTMNGD MRMQRELVYA RGDGPGAPRP GSTAHPPHAI PNSPPSTPVP HSMPPSPSRI PYGGTRSMVV PGNATIPRDR ISSLPVSRPI SPSPSAILER RDVKPDEDMS GKNIAMYRNE GFYADPYLYH EGRMSIASSH GGHPLDVPDH IIAYHRTAIR SASAYCNPSM QAEMHMEQSL YRQKSRKYPD SHLPTLGSKT PPASPHRVSD LRMIDMHAHY NAHGPPHTMQ PDRASPSRQA FKKEPGTLVY IEKPRSAAGL SSLVDLGPPL MEKQVFAYST ATIPKDRETS EKMMKTTANR NHTDSAGTPH VSGGKMLSAL ESTVPPSQPP PVGTSAIHMS LLEMRRSVAE LRLQLQQMRQ LQLQNQELLR AMMKKAELEI SGKVMETMKR LEDPVQRQRV LVEQERQKYL HEEEKIVKKL CELEDFVEDL KKDSTAASRL VTLKDVEDGA FLLRQVGEAV ATLKGEFPTL QNKMRAILRI EVEAVRFLKE EPHKLDSLLK RVRSMTDVLT MLRRHVTDGL LKGTDAAQAA QYMAMEKATA AEVLKSQEEA AHTSGQPFHS TGAPGDAKSE VVPLSGMMVR HAQSSPVVIQ PSQHSVALLN PAQNLPHVAS SPAVPQEATS TLQMSQAPQS PQIPMNGSAM QSLFIEEIHS VSAKNRAVSI EKA //