ID Q5T413_HUMAN Unreviewed; 291 AA. AC Q5T413; DT 21-DEC-2004, integrated into UniProtKB/TrEMBL. DT 21-DEC-2004, sequence version 1. DT 24-NOV-2009, entry version 38. DE SubName: Full=MutY homolog (E. coli); DE Flags: Fragment; GN Name=MUTYH; ORFNames=RP4-534D1.2-019; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RA Johnson C.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL359540; CAI21715.1; -; Genomic_DNA. DR IPI; IPI00746950; -. DR UniGene; Hs.271353; -. DR STRING; Q5T413; -. DR Ensembl; ENST00000359291; ENSP00000352239; ENSG00000132781; Homo sapiens. DR Ensembl; ENST00000372098; ENSP00000361170; ENSG00000132781; Homo sapiens. DR Ensembl; ENST00000435155; ENSP00000403655; ENSG00000132781; Homo sapiens. DR Ensembl; ENST00000448481; ENSP00000409718; ENSG00000132781; Homo sapiens. DR HGNC; HGNC:7527; MUTYH. DR HOVERGEN; Q5T413; -. DR PhylomeDB; Q5T413; -. DR ArrayExpress; Q5T413; -. DR Bgee; Q5T413; -. DR GO; GO:0005622; C:intracellular; IEA:InterPro. DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro. DR GO; GO:0006284; P:base-excision repair; IEA:InterPro. DR InterPro; IPR011257; DNA_glycosylase. DR InterPro; IPR004036; Endonuclease-III_CS2. DR InterPro; IPR004035; Endouclease-III_FeS-bd_BS. DR InterPro; IPR003651; Endouclease3_FeS-loop_motif. DR InterPro; IPR003265; HhH-GPD_domain. DR InterPro; IPR000445; HhH_motif. DR Pfam; PF10576; EndIII_4Fe-2S; 1. DR Pfam; PF00633; HHH; 1. DR Pfam; PF00730; HhH-GPD; 1. DR SMART; SM00478; ENDO3c; 1. DR SMART; SM00525; FES; 1. DR PROSITE; PS00764; ENDONUCLEASE_III_1; 1. DR PROSITE; PS01155; ENDONUCLEASE_III_2; 1. PE 2: Evidence at transcript level; FT NON_TER 291 291 SQ SEQUENCE 291 AA; 31881 MW; 28B90F48B4DBA69D CRC64; MRKPRAAVGS GHRKQAASQE GRQKHAKNNS QAKPSACDGM IAECPGAPAG LARQPEEVVL QASVSSYHLF RDVAEVTAFR GSLLSWYDQE KRDLPWRRRA EDEMDLDRRA YAVWVSEVML QQTQVATVIN YYTGWMQKWP TLQDLASASL EEVNQLWAGL GYYSRGRRLQ EGARKVVEEL GGHMPRTAET LQQLLPGVGR YTAGAIASIA FGQATGVVDG NVARVLCRVR AIGADPSSTL VSQQLWGLAQ QLVDPARPGD FNQAAMELGA TVCTPQRPLC SQCPVESLCR A //