ID Q5SVI9_MOUSE Unreviewed; 479 AA. AC Q5SVI9; DT 21-DEC-2004, integrated into UniProtKB/TrEMBL. DT 21-DEC-2004, sequence version 1. DT 31-OCT-2012, entry version 85. DE SubName: Full=Calcium/calmodulin-dependent protein kinase II, beta; DE SubName: Full=Calcium/calmodulin-dependent protein kinase type II subunit beta; GN Name=Camk2b; ORFNames=RP23-340E18.5-001; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP NUCLEOTIDE SEQUENCE. RA Collins J.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Howden P.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [4] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- SIMILARITY: Contains 1 protein kinase domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL611926; CAI24952.1; -; Genomic_DNA. DR EMBL; AL645469; CAI24952.1; JOINED; Genomic_DNA. DR EMBL; AL645469; CAI25262.1; -; Genomic_DNA. DR EMBL; AL611926; CAI25262.1; JOINED; Genomic_DNA. DR IPI; IPI00515172; -. DR UniGene; Mm.439733; -. DR SMR; Q5SVI9; 8-474. DR STRING; Q5SVI9; -. DR PRIDE; Q5SVI9; -. DR Ensembl; ENSMUST00000066431; ENSMUSP00000065101; ENSMUSG00000057897. DR MGI; MGI:88257; Camk2b. DR GeneTree; ENSGT00680000099653; -. DR HOGENOM; HOG000233016; -. DR HOVERGEN; HBG108055; -. DR ArrayExpress; Q5SVI9; -. DR Genevestigator; Q5SVI9; -. DR GO; GO:0005829; C:cytosol; IDA:MGI. DR GO; GO:0051233; C:spindle midzone; IDA:MGI. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI. DR GO; GO:0060466; P:activation of meiosis involved in egg activation; IMP:MGI. DR GO; GO:0006816; P:calcium ion transport; IMP:MGI. DR GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI. DR GO; GO:0031558; P:induction of apoptosis in response to chemical stimulus; IDA:MGI. DR GO; GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IDA:MGI. DR GO; GO:0050885; P:neuromuscular process controlling balance; IMP:MGI. DR GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI. DR GO; GO:0046777; P:protein autophosphorylation; IMP:MGI. DR GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI. DR GO; GO:0032222; P:regulation of synaptic transmission, cholinergic; IMP:MGI. DR GO; GO:0046686; P:response to cadmium ion; IDA:MGI. DR InterPro; IPR020636; Ca/CaM-dep_Ca-dep_prot_Kinase. DR InterPro; IPR013543; Ca/CaM-dep_prot_kinase-assoc. DR InterPro; IPR011009; Kinase-like_dom. DR InterPro; IPR000719; Prot_kinase_cat_dom. DR InterPro; IPR017441; Protein_kinase_ATP_BS. DR InterPro; IPR002290; Ser/Thr_dual-sp_kinase_dom. DR InterPro; IPR008271; Ser/Thr_kinase_AS. DR PANTHER; PTHR24347; PTHR24347; 1. DR Pfam; PF08332; CaMKII_AD; 1. DR Pfam; PF00069; Pkinase; 1. DR SMART; SM00220; S_TKc; 1. DR SUPFAM; SSF56112; Kinase_like; 1. DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1. PE 2: Evidence at transcript level; KW ATP-binding; Complete proteome; Kinase; Nucleotide-binding; KW Reference proteome; Serine/threonine-protein kinase; Transferase. SQ SEQUENCE 479 AA; 54104 MW; 12F45B7A66AA83AD CRC64; MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LNKKADGVKE SSDSTNTTIE DEDAKARKQE IIKTTEQLIE AVNNGDFEAY AKICDPGLTS FEPEALGNLV EGMDFHRFYF ENLLAKNSKP IHTTILNPHV HVIGEDAACI AYIRLTQYID GQGRPRTSQS EETRVWHRRD GKWQNVHFHC SGAPVAPLQ //