ID Q5SUW3_MOUSE Unreviewed; 550 AA. AC Q5SUW3; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 09-JAN-2013, entry version 35. DE SubName: Full=Growth factor receptor bound protein 10; DE SubName: Full=Growth factor receptor-bound protein 10; GN Name=Grb10; ORFNames=RP23-119N24.1-004; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP NUCLEOTIDE SEQUENCE. RA Sycamore N.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Griffiths C.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [4] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL645803; CAI23989.1; -; Genomic_DNA. DR EMBL; AL663087; CAI23989.1; JOINED; Genomic_DNA. DR EMBL; AL663087; CAI25686.1; -; Genomic_DNA. DR EMBL; AL645803; CAI25686.1; JOINED; Genomic_DNA. DR IPI; IPI00267579; -. DR UniGene; Mm.273117; -. DR UniGene; Mm.464229; -. DR SMR; Q5SUW3; 171-365, 385-421, 443-549. DR STRING; Q5SUW3; -. DR Ensembl; ENSMUST00000109653; ENSMUSP00000105280; ENSMUSG00000020176. DR MGI; MGI:103232; Grb10. DR GeneTree; ENSGT00550000074537; -. DR HOGENOM; HOG000231904; -. DR HOVERGEN; HBG000468; -. DR ArrayExpress; Q5SUW3; -. DR Genevestigator; Q5SUW3; -. DR GO; GO:0005829; C:cytosol; TAS:MGI. DR GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI. DR GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:MGI. DR Gene3D; 3.30.505.10; SH2; 1. DR InterPro; IPR015042; BPS-dom. DR InterPro; IPR000159; Ras-assoc. DR InterPro; IPR000980; SH2. DR Pfam; PF08947; BPS; 1. DR Pfam; PF00788; RA; 1. DR Pfam; PF00017; SH2; 1. DR PRINTS; PR00401; SH2DOMAIN. DR SMART; SM00314; RA; 1. DR SMART; SM00252; SH2; 1. DR PROSITE; PS50200; RA; 1. DR PROSITE; PS50001; SH2; 1. PE 2: Evidence at transcript level; KW Complete proteome; Receptor; Reference proteome. SQ SEQUENCE 550 AA; 62259 MW; 9C5F174B6F02D593 CRC64; MNNDINSSVE SLNSACNMQS DTDTAPLLED GQHASNQGAA SSSRGQPQAS PRQKMQRSQP VHILRRLQEE DQQLRTASLP AIPNPFPELT GAAPGSPPSV APSSLPPPPS QPPAKHFPPG FQLSKLTRPG LWTKTTARFS KKQPKNQCPT DTVNPVARMP TSQMEKLRLR KDVKVFSEDG TSKVVEILTD MTARDLCQLL VYKSHCVDDN SWTLVEHHPQ LGLERCLEDH EIVVQVESTM PSESKFLFRK NYAKYEFFKN PVNFFPDQMV NWCQQSNGGQ AQLLQEPRHL QLLADLEESS IFYLIAGKKQ YNAPNEHGMC IKPNKAKTEM KELRLLCAED EQIRTCWMTA FRLLKYGMLL YQNYRIPQRK GLPPPFNAPM RSVSENSLVA MDFSGQIGRV IDNPAEAQSA ALEEGHAWRK RSTRMNILSS QSPLHPSTLN AVIHRTQHWF HGRISREESH RIIKQQGLVD GLFLLRDSQS NPKAFVLTLC HHQKIKNFQI LPCEDDGQTF FTLDDGNTKF SDLIQLVDFY QLNKGVLPCK LKHHCIRVAL //