ID Q5R6G0_PONPY PRELIMINARY; PRT; 375 AA. AC Q5R6G0; DT 01-FEB-2005 (TrEMBLrel. 29, Created) DT 01-FEB-2005 (TrEMBLrel. 29, Last sequence update) DT 01-FEB-2005 (TrEMBLrel. 29, Last annotation update) DE Hypothetical protein DKFZp459A127. GN Name=DKFZp459A127; OS Pongo pygmaeus (Orangutan). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Pongo. OX NCBI_TaxID=9600; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Cortex; RG The German cDNA Consortium; RA Ottenwaelder B., Obermaier B., Deutschenbaur S., Schaipp A., RA Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.; RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Actins are highly conserved proteins that are involved CC in various types of cell motility and are ubiquitously expressed CC in all eukaryotic cells (By similarity). CC -!- SUBUNIT: Polymerization of globular actin (G-actin) leads to a CC structural filament (F-actin) in the form of a two-stranded helix. CC Each actin can bind to 4 others (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasmic (By similarity). CC -!- SIMILARITY: Belongs to the actin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CR860530; CAH92656.1; -. DR GO; GO:0005884; C:actin filament; IEA. DR GO; GO:0003774; F:motor activity; IEA. DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA. DR InterPro; IPR004001; Actin. DR InterPro; IPR004000; Actin_like. DR Pfam; PF00022; Actin; 1. DR PRINTS; PR00190; ACTIN. DR SMART; SM00268; ACTIN; 1. DR PROSITE; PS00406; ACTINS_1; 1. DR PROSITE; PS00432; ACTINS_2; 1. DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1. KW Hypothetical protein; Structural protein. SQ SEQUENCE 375 AA; 41736 MW; 6AFD05CA94E360E2 CRC64; MDDDIAALVV DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF //