ID   Q5PR38_DANRE            Unreviewed;       244 AA.
AC   Q5PR38;
DT   04-JAN-2005, integrated into UniProtKB/TrEMBL.
DT   04-JAN-2005, sequence version 1.
DT   29-SEP-2021, entry version 88.
DE   SubName: Full=Zgc:123047 protein {ECO:0000313|EMBL:AAH86839.1};
DE   Flags: Fragment;
GN   Name=pcxa {ECO:0000313|ZFIN:ZDB-GENE-090908-3};
GN   Synonyms=pcl {ECO:0000313|ZFIN:ZDB-GENE-090908-3}, zgc:123047
GN   {ECO:0000313|EMBL:AAH86839.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH86839.1};
RN   [1] {ECO:0000313|EMBL:AAH86839.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Liver {ECO:0000313|EMBL:AAH86839.1};
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC086839; AAH86839.1; -; mRNA.
DR   ZFIN; ZDB-GENE-090908-3; pcxa.
DR   PhylomeDB; Q5PR38; -.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; IBA:GO_Central.
DR   GO; GO:0006094; P:gluconeogenesis; IBA:GO_Central.
DR   GO; GO:0046959; P:habituation; IMP:ZFIN.
DR   GO; GO:0006090; P:pyruvate metabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.1490.20; -; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR005481; BC-like_N.
DR   InterPro; IPR011764; Biotin_carboxylation_dom.
DR   InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   Pfam; PF00289; Biotin_carb_N; 1.
DR   Pfam; PF02786; CPSase_L_D2; 1.
DR   SUPFAM; SSF52440; SSF52440; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS50979; BC; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}.
FT   DOMAIN          22..244
FT                   /note="Biotin carboxylation"
FT                   /evidence="ECO:0000259|PROSITE:PS50979"
FT   DOMAIN          142..198
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   REGION          196..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        205..244
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         244
FT                   /evidence="ECO:0000313|EMBL:AAH86839.1"
SQ   SEQUENCE   244 AA;  27479 MW;  23C55EB157459F77 CRC64;
     MRRMWSLTRC AHTAPQALEY KPIKKVMVAN RGEIAIRVFR ACTELGIRTV AVYSEQDTGQ
     MHRQKADEAY LIGKGLPPVA AYLHIPDIIK VAKANDVDAI HPGYGFLSER ADFAQACVDA
     GVRFIGPTPD VVRKMGDKVQ ARAIAISAGV PVVPGTDAPI SCLQEAQEFS NSYGFPIIFK
     AAYGGGGRGM RVVREYEELE EQKKKKKKKK KKKKKKKKKK KKKKKKKKKK KKKKKKKKKK
     KKKK
//