ID Q5NCU3_MOUSE Unreviewed; 172 AA. AC Q5NCU3; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 11-DEC-2019, entry version 76. DE SubName: Full=SPARC {ECO:0000313|Ensembl:ENSMUSP00000119475}; DE Flags: Fragment; GN Name=Sparc {ECO:0000313|Ensembl:ENSMUSP00000119475, GN ECO:0000313|MGI:MGI:98373}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119475, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000119475, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119475, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000213|PubMed:21183079} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001; RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.; RT "A tissue-specific atlas of mouse protein phosphorylation and expression."; RL Cell 143:1174-1189(2010). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000119475} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119475}; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL596207; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL772268; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR SMR; Q5NCU3; -. DR MaxQB; Q5NCU3; -. DR PeptideAtlas; Q5NCU3; -. DR PRIDE; Q5NCU3; -. DR Ensembl; ENSMUST00000141530; ENSMUSP00000119475; ENSMUSG00000018593. DR MGI; MGI:98373; Sparc. DR GeneTree; ENSGT00510000046787; -. DR HOGENOM; HOG000088654; -. DR ChiTaRS; Sparc; mouse. DR Proteomes; UP000000589; Chromosome 11. DR Bgee; ENSMUSG00000018593; Expressed in 324 organ(s), highest expression level in vault of skull. DR ExpressionAtlas; Q5NCU3; baseline and differential. DR GO; GO:0062023; C:collagen-containing extracellular matrix; IEA:InterPro. DR GO; GO:0005615; C:extracellular space; IEA:InterPro. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR GO; GO:0005518; F:collagen binding; IEA:InterPro. DR InterPro; IPR003645; Fol_N. DR InterPro; IPR015369; Follistatin/Osteonectin_EGF. DR InterPro; IPR002350; Kazal_dom. DR InterPro; IPR036058; Kazal_dom_sf. DR InterPro; IPR001999; Osteonectin_CS. DR InterPro; IPR037641; SPARC. DR PANTHER; PTHR13866:SF6; PTHR13866:SF6; 1. DR Pfam; PF09289; FOLN; 1. DR Pfam; PF00050; Kazal_1; 1. DR SMART; SM00274; FOLN; 1. DR SMART; SM00280; KAZAL; 1. DR SUPFAM; SSF100895; SSF100895; 1. DR PROSITE; PS51465; KAZAL_2; 1. DR PROSITE; PS00612; OSTEONECTIN_1; 1. DR PROSITE; PS00613; OSTEONECTIN_2; 1. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0000213|EPD:Q5NCU3, KW ECO:0000213|MaxQB:Q5NCU3, ECO:0000213|PeptideAtlas:Q5NCU3}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1..17 FT /evidence="ECO:0000256|SAM:SignalP" FT CHAIN 18..172 FT /evidence="ECO:0000256|SAM:SignalP" FT /id="PRO_5004260259" FT DOMAIN 91..148 FT /note="Kazal-like" FT /evidence="ECO:0000259|PROSITE:PS51465" FT NON_TER 172 FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000119475" SQ SEQUENCE 172 AA; 19096 MW; CAEEDC2D79984AF0 CRC64; MRAWIFFLLC LAGRALAAPT EVAEEIVEEE TVVEETGVPV GANPVQVEMG EFEDGAEETV EEVVADNPCQ NHHCKHGKVC ELDESNTPMC VCQDPTSCPA PIGEFEKVCS NDNKTFDSSC HFFATKCTLE GTKKGHKLHL DYIGPCKYIA PCLDSELTEF PLRMRDWLKN VL //