ID Q5MKL4_HUMAN PRELIMINARY; PRT; 276 AA. AC Q5MKL4; DT 01-FEB-2005, integrated into UniProtKB/TrEMBL. DT 01-FEB-2005, sequence version 1. DT 13-JUN-2006, entry version 15. DE Signal-regulatory protein beta 2 isoform 3.2 (Signal-regulatory DE protein beta 2 isoform 3.1). OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=21036165; PubMed=11185750; DOI=10.1007/s100380070013; RA Ichigotani Y., Matsuda S., Machida K., Oshima K., Iwamoto T., RA Yamaki K., Hayakawa T., Hamaguchi M.; RT "Molecular cloning of a novel human gene (SIRP-B2) which encodes a new RT member of the SIRP/SHPS-1 protein family."; RL J. Hum. Genet. 45:378-382(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RX PubMed=15383453; DOI=10.1182/blood-2004-07-2823; RA Piccio L., Vermi W., Boles K.S., Fuchs A., Strader C.A., Facchetti F., RA Cella M., Colonna M.; RT "Adhesion of human T cells to antigen-presenting cells through RT SIRP{beta}2-CD47 interaction costimulates T cell proliferation."; RL Blood 105:2421-2427(2005). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY748248; AAV88531.1; -; mRNA. DR EMBL; AY748247; AAV88530.1; -; mRNA. DR Ensembl; ENSG00000089012; Homo sapiens. DR GO; GO:0016021; C:integral to membrane; IEA. DR GO; GO:0016020; C:membrane; IEA. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR003597; Ig_C1-set. DR InterPro; IPR003599; Ig_sub. DR InterPro; IPR013106; Ig_V-set. DR Pfam; PF07654; C1-set; 1. DR Pfam; PF07686; V-set; 1. DR SMART; SM00409; IG; 1. DR SMART; SM00407; IGc1; 1. DR PROSITE; PS50835; IG_LIKE; 2. KW Immunoglobulin domain; Membrane; Repeat; Transmembrane. SQ SEQUENCE 276 AA; 29967 MW; AF76A8692051D6C1 CRC64; MPVPASWPHP PGPFLLLTLL LGLTEVAGEE ELQMIQPEKL LLVTVGKTAT LHCTVTSLLP VGPVLWFRGV GPGRELIYNQ KEGHFPRVTT VSDLTKRNNM DFSIRISSIT PADVGTYYCV KFRKGSPENV EFKSGPGTEM ALGAKPSAPV VLGPAARTTP EHTVSFTCES HGFSPRDITL KWFKNGNELS DFQTNVDPTG QSVAYSIRST ARVVLDPWDV RSQVICEVAH VTLQGDPLRG TANLSEAIRG PASSLTALLL IAVLLGPIYV PWKQKT //