ID Q5K1I2_9MUSC Unreviewed; 236 AA. AC Q5K1I2; DT 15-FEB-2005, integrated into UniProtKB/TrEMBL. DT 15-FEB-2005, sequence version 1. DT 25-OCT-2017, entry version 86. DE RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(+)] {ECO:0000256|RuleBase:RU361243}; DE EC=1.1.1.8 {ECO:0000256|RuleBase:RU361243}; DE Flags: Fragment; GN Name=Gpdh {ECO:0000313|FlyBase:FBgn0083660}; OS Drosophila malerkotliana malerkotliana. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=195057 {ECO:0000313|EMBL:CAH60229.1}; RN [1] {ECO:0000313|EMBL:CAH60229.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=391.0 {ECO:0000313|EMBL:CAH60229.1}, 391.1 RC {ECO:0000313|EMBL:CAH60230.1}, Cjb185 {ECO:0000313|EMBL:CAH60233.1}, RC Mys96 {ECO:0000313|EMBL:CAH60234.1}, and Swb17 RC {ECO:0000313|EMBL:CAH60231.1}; RA Kopp A., Barmina O.; RT "Evolutionary history of the Drosophila bipectinata species complex."; RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + NAD(+) = glycerone CC phosphate + NADH. {ECO:0000256|RuleBase:RU361243}. CC -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate CC dehydrogenase family. {ECO:0000256|RuleBase:RU000437}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ844732; CAH60229.1; -; Genomic_DNA. DR EMBL; AJ844733; CAH60230.1; -; Genomic_DNA. DR EMBL; AJ844734; CAH60231.1; -; Genomic_DNA. DR EMBL; AJ844736; CAH60233.1; -; Genomic_DNA. DR EMBL; AJ844737; CAH60234.1; -; Genomic_DNA. DR ProteinModelPortal; Q5K1I2; -. DR FlyBase; FBgn0083660; Dmmm\Gpdh. DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:UniProtKB-UniRule. DR GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; IEA:UniProtKB-UniRule. DR GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule. DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:UniProtKB-UniRule. DR Gene3D; 1.10.1040.10; -; 1. DR InterPro; IPR008927; 6-PGluconate_DH_C-like. DR InterPro; IPR013328; 6PGD_dom_2. DR InterPro; IPR006168; G3P_DH_NAD-dep. DR InterPro; IPR006109; G3P_DH_NAD-dep_C. DR InterPro; IPR017751; G3P_DH_NAD-dep_euk. DR InterPro; IPR011128; G3P_DH_NAD-dep_N. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR Pfam; PF07479; NAD_Gly3P_dh_C; 1. DR Pfam; PF01210; NAD_Gly3P_dh_N; 1. DR PRINTS; PR00077; GPDHDRGNASE. DR SUPFAM; SSF48179; SSF48179; 1. DR SUPFAM; SSF51735; SSF51735; 1. DR TIGRFAMs; TIGR03376; glycerol3P_DH; 1. DR PROSITE; PS00957; NAD_G3PDH; 1. PE 3: Inferred from homology; KW NAD {ECO:0000256|RuleBase:RU000437}; KW Oxidoreductase {ECO:0000256|RuleBase:RU000437}. FT DOMAIN 1 90 NAD_Gly3P_dh_N. {ECO:0000259|Pfam: FT PF01210}. FT DOMAIN 111 233 NAD_Gly3P_dh_C. {ECO:0000259|Pfam: FT PF07479}. FT NON_TER 1 1 {ECO:0000313|EMBL:CAH60229.1}. FT NON_TER 236 236 {ECO:0000313|EMBL:CAH60229.1}. SQ SEQUENCE 236 AA; 25567 MW; 6D161CD5785BFC08 CRC64; VPHQFIPNFC KQLLGKIKPN AIAISLIKGF DKAEGGGIDL ISHIITRHLK VSVPRKGDQI PCAVLMGANL ANEVAEGNFC ETTIGCTDKK YGKVLRDLFQ ANHFRVVVVD DADAVEVCGA LKNIVACGAG FVDGLKLGDN TKAAVIRLGL MEMIRFVDVF YPGSKLSTFF ESCGVADLIT TCYGGGRNRR VSEAFVTSGK TIEELEKEML NGQKLQGPPT AEEVNYMLKN KGLEDK //