ID Q5JRY3_HUMAN Unreviewed; 120 AA. AC Q5JRY3; DT 15-FEB-2005, integrated into UniProtKB/TrEMBL. DT 15-FEB-2005, sequence version 1. DT 05-SEP-2012, entry version 48. DE SubName: Full=Transcription factor 7-like 2; DE SubName: Full=Transcription factor 7-like 2 (T-cell specific, HMG-box); GN Name=TCF7L2; ORFNames=RP11-357H24.1-006; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15164054; DOI=10.1038/nature02462; RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P., RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., RA Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., RA Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., RA Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., RA Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., RA Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., RA Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., RA Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., RA Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., RA Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., RA Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., RA Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., RA Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., RA Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., RA Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., RA Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., RA Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., RA Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., RA Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., RA Doucette-Stamm L., Beck S., Smith D.R., Rogers J.; RT "The DNA sequence and comparative analysis of human chromosome 10."; RL Nature 429:375-381(2004). RN [2] RP NUCLEOTIDE SEQUENCE. RA Holt K.; RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases. RN [3] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL135792; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL158212; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL445486; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AL451084; CAI40406.1; -; Genomic_DNA. DR IPI; IPI00552531; -. DR UniGene; Hs.593995; -. DR ProteinModelPortal; Q5JRY3; -. DR SMR; Q5JRY3; 1-75. DR STRING; Q5JRY3; -. DR Ensembl; ENST00000369386; ENSP00000358393; ENSG00000148737. DR HGNC; HGNC:11641; TCF7L2. DR GeneTree; ENSGT00390000009964; -. DR HOGENOM; HOG000116032; -. DR HOVERGEN; HBG000419; -. DR ArrayExpress; Q5JRY3; -. DR Bgee; Q5JRY3; -. DR GO; GO:0016055; P:Wnt receptor signaling pathway; IEA:InterPro. DR Gene3D; G3DSA:1.10.30.10; HMG-box; 1. DR InterPro; IPR009071; HMG_superfamily. DR InterPro; IPR024940; TCF/LEF. DR PANTHER; PTHR10373; PTHR10373; 1. DR Pfam; PF00505; HMG_box; 1. DR SMART; SM00398; HMG; 1. DR SUPFAM; SSF47095; HMG-box; 1. DR PROSITE; PS50118; HMG_BOX_2; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 120 AA; 14097 MW; 4502C0DEC3C059EA CRC64; MLYMKEMRAK VVAECTLKES AAINQILGRR WHALSREEQA KYYELARKER QLHMQLYPGW SARDNYGKKK KRKRDKQPGE TNDLSAPKKC RARFGLDQQN NWCGPCRCKY SKEVSGTVRA //