ID Q5JPG0_HUMAN Unreviewed; 510 AA. AC Q5JPG0; DT 15-FEB-2005, integrated into UniProtKB/TrEMBL. DT 15-FEB-2005, sequence version 1. DT 04-DEC-2007, entry version 31. DE Putative uncharacterized protein DKFZp667L2223 (cDNA FLJ76069, highly DE similar to Homo sapiens zinc finger protein 75 (D8C6) (ZNF75), mRNA) DE (Zinc finger protein 75) (D8C6). GN Name=DKFZp667L2223; Synonyms=ZNF75; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Lymph node; RG The German cDNA Consortium; RA Ansorge W., Krieger S., Regiert T., Rittmueller C., Schwager B., RA Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.; RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Thalamus; RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=PCR rescued clones; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [4] RP NUCLEOTIDE SEQUENCE. RC TISSUE=PCR rescued clones; RG NIH MGC Project; RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains 1 SCAN box domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC109100; AAI09101.1; -; mRNA. DR EMBL; AK290215; BAF82904.1; -; mRNA. DR EMBL; AL832801; CAI46130.1; -; mRNA. DR RefSeq; NP_009062.2; -. DR UniGene; Hs.533540; -. DR UniGene; Hs.667773; -. DR Ensembl; ENSG00000186376; Homo sapiens. DR GeneID; 7626; -. DR KEGG; hsa:7626; -. DR HGNC; HGNC:13145; ZNF75. DR ArrayExpress; Q5JPG0; -. DR GO; GO:0005634; C:nucleus; IEA:InterPro. DR GO; GO:0003700; F:transcription factor activity; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR InterPro; IPR001909; KRAB. DR InterPro; IPR003309; Treg_SCAN. DR InterPro; IPR007087; Znf_C2H2. DR InterPro; IPR015880; Znf_C2H2-like. DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd. DR InterPro; IPR007086; Znf_C2H2_sub. DR Gene3D; G3DSA:3.30.160.60; G3DSA:3.30.160.60; 4. DR Pfam; PF01352; KRAB; 1. DR Pfam; PF02023; SCAN; 1. DR Pfam; PF00096; zf-C2H2; 5. DR PRINTS; PR00048; ZINCFINGER. DR ProDom; PD000003; Znf_C2H2; 3. DR SMART; SM00349; KRAB; 1. DR SMART; SM00431; SCAN; 1. DR SMART; SM00355; ZnF_C2H2; 5. DR PROSITE; PS50805; KRAB; 1. DR PROSITE; PS50804; SCAN_BOX; 1. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; UNKNOWN_5. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5. PE 2: Evidence at transcript level; KW DNA-binding; Metal-binding; Nucleus; Transcription; KW Transcription regulation; Zinc; Zinc-finger. SQ SEQUENCE 510 AA; 59298 MW; 37D405F102965A24 CRC64; MAMRELNADS CSSPQMGAMW ETSGSVKENS SQSKKYSTKI ENLGPESACR HFWSFRYHEA TGPLETISQL QKLCHQWLRP EIHSKEQILE MLVLEQFLSI LPKETQNWVQ KHHPQNVKQA LVLVEFLQRE PDGTKNEVTA HELGKEAVLL GGTAVAPGFK WKPAEPQPMG VFQKEYWNTY RVLQEQLGWN THKETQPVYE RAVHDQQMLA LSEQKRIKHW KMASKLILPE SLSLLTFEDV AVYFSEEEWQ LLNPLEKTLY NDVMQDIYET VISLGLKLKN DTGNDHPISV STSEIQTSGC EVSKKTRMKI AQKTMGRENP GDTHSVQKWH RAFPRKKRKK PATCKQELPK LMDLHGKGPT GEKPFKCQEC GKSFRVSSDL IKHHRIHTGE KPYKCQQCDR RFRWSSDLNK HFMTHQGIKP YRCSWCGKSF SHNTNLHTHQ RIHTGEKPFK CDECGKRFIQ NSHLIKHQRT HTGEQPYTCS LCKRNFSRRS SLLRHQKLHR RREACLVSPN //