ID Q5JPG0_HUMAN PRELIMINARY; PRT; 510 AA. AC Q5JPG0; DT 15-FEB-2005, integrated into UniProtKB/TrEMBL. DT 15-FEB-2005, sequence version 1. DT 04-APR-2006, entry version 10. DE Hypothetical protein DKFZp667L2223 (Zinc finger protein 75). GN Name=DKFZp667L2223; Synonyms=ZNF75; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Lymph node; RG The German cDNA Consortium; RA Ansorge W., Krieger S., Regiert T., Rittmueller C., Schwager B., RA Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.; RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=PCR rescued clones; RX MEDLINE=22388257; PubMed=12477932; DOI=10.1073/pnas.242603899; RA Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., RA Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., RA Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., RA Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., RA Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., RA Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., RA Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., RA Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., RA Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., RA Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., RA Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., RA Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., RA Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., RA Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., RA Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., RA Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., RA Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.; RT "Generation and initial analysis of more than 15,000 full-length human RT and mouse cDNA sequences."; RL Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=PCR rescued clones; RG NIH MGC Project; RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Nuclear (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL832801; CAI46130.1; -; mRNA. DR EMBL; BC109100; AAI09101.1; -; mRNA. DR UniGene; Hs.533540; -. DR Ensembl; ENSG00000186376; Homo sapiens. DR GO; GO:0005634; C:nucleus; IEA. DR GO; GO:0003676; F:nucleic acid binding; IEA. DR GO; GO:0003700; F:transcription factor activity; IEA. DR GO; GO:0008270; F:zinc ion binding; IEA. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA. DR InterPro; IPR001909; KRAB. DR InterPro; IPR003309; Treg_SCAN. DR InterPro; IPR007087; Znf_C2H2. DR InterPro; IPR007086; Znf_C2H2_sub. DR Pfam; PF01352; KRAB; 1. DR Pfam; PF02023; SCAN; 1. DR Pfam; PF00096; zf-C2H2; 5. DR PRINTS; PR00048; ZINCFINGER. DR ProDom; PD000003; Znf_C2H2; 4. DR SMART; SM00349; KRAB; 1. DR SMART; SM00431; LER; 1. DR SMART; SM00355; ZnF_C2H2; 5. DR PROSITE; PS50805; KRAB; 1. DR PROSITE; PS50804; SCAN_BOX; 1. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5. KW Hypothetical protein; Metal-binding; Nuclear protein; Zinc; KW Zinc-finger. SQ SEQUENCE 510 AA; 59298 MW; 37D405F102965A24 CRC64; MAMRELNADS CSSPQMGAMW ETSGSVKENS SQSKKYSTKI ENLGPESACR HFWSFRYHEA TGPLETISQL QKLCHQWLRP EIHSKEQILE MLVLEQFLSI LPKETQNWVQ KHHPQNVKQA LVLVEFLQRE PDGTKNEVTA HELGKEAVLL GGTAVAPGFK WKPAEPQPMG VFQKEYWNTY RVLQEQLGWN THKETQPVYE RAVHDQQMLA LSEQKRIKHW KMASKLILPE SLSLLTFEDV AVYFSEEEWQ LLNPLEKTLY NDVMQDIYET VISLGLKLKN DTGNDHPISV STSEIQTSGC EVSKKTRMKI AQKTMGRENP GDTHSVQKWH RAFPRKKRKK PATCKQELPK LMDLHGKGPT GEKPFKCQEC GKSFRVSSDL IKHHRIHTGE KPYKCQQCDR RFRWSSDLNK HFMTHQGIKP YRCSWCGKSF SHNTNLHTHQ RIHTGEKPFK CDECGKRFIQ NSHLIKHQRT HTGEQPYTCS LCKRNFSRRS SLLRHQKLHR RREACLVSPN //