ID Q5IJK6_9NEOP PRELIMINARY; PRT; 267 AA. AC Q5IJK6; DT 10-MAY-2005 (TrEMBLrel. 30, Created) DT 10-MAY-2005 (TrEMBLrel. 30, Last sequence update) DT 10-MAY-2005 (TrEMBLrel. 30, Last annotation update) DE Cytochrome oxidase subunit I (Fragment). GN Name=COI; OS Ithomia hyala hyala. OG Mitochondrion. OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Papilionoidea; Nymphalidae; Danainae; Ithomiini; Ithomia. OX NCBI_TaxID=305997; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=15683934; DOI=10.1016/j.ympev.2004.10.021; RA Mallarino R., Bermingham E., Willmott K.R., Whinnett A., Jiggins C.D.; RT "Molecular systematics of the butterfly genus Ithomia (Lepidoptera: RT Ithomiinae): a composite phylogenetic hypothesis based on seven RT genes."; RL Mol. Phylogenet. Evol. 34:625-644(2005). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) = 4 ferricytochrome CC c + 2 H(2)O. CC -!- PATHWAY: Respiratory chain; terminal step. CC -!- SUBCELLULAR LOCATION: Integral membrane protein. Mitochondrial CC inner membrane (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY713056; AAW56248.1; -; Genomic_DNA. DR EMBL; AY713055; AAW56246.1; -; Genomic_DNA. DR GO; GO:0019866; C:inner membrane; IEA. DR GO; GO:0016021; C:integral to membrane; IEA. DR GO; GO:0005746; C:mitochondrial electron transport chain; IEA. DR GO; GO:0005739; C:mitochondrion; IEA. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA. DR GO; GO:0016491; F:oxidoreductase activity; IEA. DR GO; GO:0006118; P:electron transport; IEA. DR GO; GO:0006810; P:transport; IEA. DR InterPro; IPR000883; COX1. DR PANTHER; PTHR10422; COX1; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR PROSITE; PS50855; COX1; 1. KW Copper; Electron transport; Heme; Inner membrane; Membrane; KW Mitochondrion; Oxidoreductase; Respiratory chain; Transmembrane; KW Transport. FT NON_TER 1 1 SQ SEQUENCE 267 AA; 30121 MW; A925318FCBE86754 CRC64; LPGFGMISHI ISQESGKKET FGSLGMIYAM MAIGLLGFIV WAHHMFTVGM DIDTRAYFTS ATMIIAVPTG IKIFSWLATL HGTQINYSPS ILWSLGFVFL FTVGGLTGVI LANSSIDITL HDTYYVVAHF HYVLSMGAVF AILGGFIHWY PLFTGLILNP YLLKIQFFTM FLGVNITFFP QHFLGLAGMP RRYSDYPDSF MSWNIISSLG SYISLLSMMM IIIIIWESMI NQRIILFSLN MPSSIEWYQN LPPAEHSYNE LPILSNF //