ID   Q5IJJ0_9NEOP            Unreviewed;       269 AA.
AC   Q5IJJ0;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   08-JUN-2016, entry version 59.
DE   RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
DE            EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
DE   Flags: Fragment;
GN   Name=COI {ECO:0000313|EMBL:AAW56264.1};
OS   Ithomia iphianassa panamensis.
OG   Mitochondrion {ECO:0000313|EMBL:AAW56264.1}.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia;
OC   Papilionoidea; Nymphalidae; Danainae; Ithomiini; Ithomiina; Ithomia.
OX   NCBI_TaxID=306001 {ECO:0000313|EMBL:AAW56264.1};
RN   [1] {ECO:0000313|EMBL:AAW56264.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15683934; DOI=10.1016/j.ympev.2004.10.021;
RA   Mallarino R., Bermingham E., Willmott K.R., Whinnett A., Jiggins C.D.;
RT   "Molecular systematics of the butterfly genus Ithomia (Lepidoptera:
RT   Ithomiinae): a composite phylogenetic hypothesis based on seven
RT   genes.";
RL   Mol. Phylogenet. Evol. 34:625-644(2005).
CC   -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
CC       chain that catalyzes the reduction of oxygen to water. Subunits 1-
CC       3 form the functional core of the enzyme complex. CO I is the
CC       catalytic subunit of the enzyme. Electrons originating in
CC       cytochrome c are transferred via the copper A center of subunit 2
CC       and heme A of subunit 1 to the bimetallic center formed by heme A3
CC       and copper B. {ECO:0000256|RuleBase:RU000369}.
CC   -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
CC       ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
CC   -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
CC       {ECO:0000256|RuleBase:RU000369}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU000369}.
CC   -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC       {ECO:0000256|RuleBase:RU000369}.
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DR   EMBL; AY713064; AAW56264.1; -; Genomic_DNA.
DR   EMBL; AY713065; AAW56266.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q5IJJ0; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.210.10; -; 1.
DR   InterPro; IPR000883; COX1.
DR   InterPro; IPR023616; Cyt_c_Oxase_su1_dom.
DR   PANTHER; PTHR10422; PTHR10422; 1.
DR   Pfam; PF00115; COX1; 1.
DR   PRINTS; PR01165; CYCOXIDASEI.
DR   SUPFAM; SSF81442; SSF81442; 1.
DR   PROSITE; PS50855; COX1; 1.
PE   3: Inferred from homology;
KW   Copper {ECO:0000256|RuleBase:RU000369};
KW   Electron transport {ECO:0000256|RuleBase:RU000369};
KW   Heme {ECO:0000256|RuleBase:RU000369};
KW   Iron {ECO:0000256|RuleBase:RU000369};
KW   Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000369};
KW   Mitochondrion {ECO:0000256|RuleBase:RU000369,
KW   ECO:0000313|EMBL:AAW56264.1};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000369};
KW   Respiratory chain {ECO:0000256|RuleBase:RU000369};
KW   Transmembrane {ECO:0000256|RuleBase:RU000369,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU000369}.
FT   TRANSMEM     23     46       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     58     81       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     93    114       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    126    151       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    163    182       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    202    228       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    267       COX1. {ECO:0000259|PROSITE:PS50855}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:AAW56264.1}.
SQ   SEQUENCE   269 AA;  30366 MW;  7079902F78F8BB63 CRC64;
     LILPGFGMIS HIISQESGKK ETFGSLGMIY AMMAIGLLGF IVWAHHMFTV GMDIDTRAYF
     TSATMIIAVP TGIKIFSWLA TLHGTQINYS PSILWSLGFV FLFTVGGLTG VILANSSIDI
     TLHDTYYVVA HFHYVLSMGA VFAILGGFIH WYPLFTGLIM NPYLLKIQFF TMFLGVNITF
     FPQHFLGLAG MPRRYSDYPD SFMSWNIISS LGSYISLLSM MMIIIIIWES MINQRIILFS
     LNMPSSIEWY QNLPPAEHSY NELPILSNF
//