ID Q5ICG6_MOUSE PRELIMINARY; PRT; 722 AA. AC Q5ICG6; DT 10-MAY-2005 (TrEMBLrel. 30, Created) DT 10-MAY-2005 (TrEMBLrel. 30, Last sequence update) DT 10-MAY-2005 (TrEMBLrel. 30, Last annotation update) DE Long chain acyl-CoA synthetase 6 isoform 2. GN Name=Acsl6; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; RX PubMed=15629433; DOI=10.1016/j.bbrc.2004.11.141; RA Lee E.J., Kim H.C., Cho Y.Y., Byun S.J., Lim J.M., Ryoo Z.Y.; RT "Alternative promotion of the mouse acyl-CoA synthetase 6 (mAcsl6) RT gene mediates the expression of multiple transcripts with 5'-end RT heterogeneity: genetic organization of mAcsl6 variants."; RL Biochem. Biophys. Res. Commun. 327:84-93(2005). CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY786361; AAW33884.1; -; mRNA. DR GO; GO:0016021; C:integral to membrane; TAS. DR GO; GO:0005739; C:mitochondrion; IDA. DR GO; GO:0004467; F:long-chain-fatty-acid-CoA ligase activity; IDA. DR GO; GO:0005515; F:protein binding; IPI. DR GO; GO:0007405; P:neuroblast proliferation; IDA. DR InterPro; IPR000873; AMP-bind. DR Pfam; PF00501; AMP-binding; 1. DR PRINTS; PR00154; AMPBINDING. DR PROSITE; PS00455; AMP_BINDING; 1. KW Fatty acid metabolism; Ligase; Lipid metabolism; Transmembrane. SQ SEQUENCE 722 AA; 80775 MW; B7DD494A0468660B CRC64; MLTFFLVSGG SLWLFAEIAL SLLEKMQTQE ILRILRLPEL SDLGQFFRSL SATTLVSVGA LAAVLAYWLT HRPKALQPPC NLLKQSEEVE DGGGARRSVI GGCTQLLTHY YDDARTMYQV FRRGLSISGN GPCLGFRKPE QPYQWLSYQE VAKRAEFLGS GLLQHDCKVG TEQFVGVFAQ NRPEWIIAEL ACYTYSMVVV PLYDTLGPGS ISYIINTADI CTVIVDKPHK ATLLLEHVER KETPGLKLVI LMEPFEDALR ERGKKCGVDI KSMQAIEDCG RENHHAPVPP RPDDLSIVCF TSGTTGNPKG AMLTHGNVVA DFSGFLKVTE KVIFPRQDDV LISFLPLAHM FERVIQSVVY CHGGRVGFFQ GDIRLLSDDM KALRPTIFSV VPRLLNRMYD KIFHQADTSL KRWLLEFAAK RKQAEVRSGI IRNNSIWDEL FFNKIQASLG GHVRMIVTGA APASPTVLGF LRAALGCQVY EGYGQTECTA GCTFTTPGDW TSGHVGAPLP CNHIKLVDAE ELNYWTCKGE GEICVKGPNV FKGYLKDEDR TKEALDSDGW LHTGDIGKWL PEGTLKIIDR KKHIFKLAQG EYVAPEKIEN IYIRSEPVAQ IYVHGDSLKA FLVGIVVPDP EVMPSWAQKK GIEGTYQELC MKKELKKAIL DDMVMLGKES GLHSFEQVKA IYIHCDMFSV QNGLLTPTLK AKRPELREYF KKQIEELYLV SV //