ID Q5EBG5_MOUSE Unreviewed; 266 AA. AC Q5EBG5; DT 15-MAR-2005, integrated into UniProtKB/TrEMBL. DT 15-MAR-2005, sequence version 1. DT 27-NOV-2024, entry version 85. DE RecName: Full=60S ribosomal protein L7a {ECO:0000256|RuleBase:RU367042}; GN Name=Rpl7a {ECO:0000313|EMBL:AAH89624.1, ECO:0000313|MGI:MGI:1353472}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH89624.1}; RN [1] {ECO:0000313|EMBL:AAH89624.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Kidney {ECO:0000313|EMBL:AAH89624.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M., RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA project: RT the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- FUNCTION: Component of the ribosome. {ECO:0000256|RuleBase:RU367042}. CC -!- SUBUNIT: Component of the large ribosomal subunit. Interacts with CRY1. CC Interacts with DICER1, AGO2, TARBP2, MOV10 and EIF6; they form a large CC RNA-induced silencing complex (RISC). {ECO:0000256|ARBA:ARBA00046616}. CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family. CC {ECO:0000256|ARBA:ARBA00007337, ECO:0000256|RuleBase:RU367042}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC089624; AAH89624.1; -; mRNA. DR AlphaFoldDB; Q5EBG5; -. DR PeptideAtlas; Q5EBG5; -. DR AGR; MGI:1353472; -. DR MGI; MGI:1353472; Rpl7a. DR ChiTaRS; Rpl7a; mouse. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:UniProtKB-UniRule. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro. DR FunFam; 3.30.1330.30:FF:000003; 60S ribosomal protein L7a; 1. DR Gene3D; 3.30.1330.30; -; 1. DR InterPro; IPR050257; eL8_RNA-proc_assembly. DR InterPro; IPR029064; Ribosomal_eL30-like_sf. DR InterPro; IPR001921; Ribosomal_eL8. DR InterPro; IPR004037; Ribosomal_eL8-like_CS. DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45. DR InterPro; IPR018492; Ribosomal_eL8/Nhp2. DR PANTHER; PTHR23105:SF218; 60S RIBOSOMAL PROTEIN L7A; 1. DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1. DR Pfam; PF01248; Ribosomal_L7Ae; 1. DR PRINTS; PR00881; L7ARS6FAMILY. DR PRINTS; PR00882; RIBOSOMALL7A. DR SUPFAM; SSF55315; L30e-like; 1. DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1. PE 2: Evidence at transcript level; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, KW ECO:0000256|RuleBase:RU367042}; KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, KW ECO:0000256|RuleBase:RU367042}. FT DOMAIN 131..212 FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45" FT /evidence="ECO:0000259|Pfam:PF01248" SQ SEQUENCE 266 AA; 29905 MW; 8237BF1CD3C51B54 CRC64; MPKGKKAKGK KVAPAPAVVK KQEAKKVVNP LFEKRPKNFG IGQDIQPKRD LTRFVKWPRY IRLQRQRAIL YKRLKVPPAI NQFTQALDRQ TATQLLKLAH KYRPETKQEK KQRLLARAEK KAAGKGDVPT KRPPVLRAGV NTVTTLVENK KAQLVVIAHD VDPIELVVFL PALCRKMGVP YCIIKGKARL GHLVHRKTCT TVAFTQVNSE DKGALAKLVG AIRTNYNDRY DEIRRHWGGN VLGPKSVARI AKLEKAKAKE LATKLG //